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The effects of UV-A light in indirect irradiation on cultures of bovine lens epithelium

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Retinal Pigment Epithelium and Macular Diseases

Part of the book series: Documenta Ophthalmologica Proceedings Series ((DOPS,volume 62))

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Abstract

Conjunctivitis, keratitis actinica, retinal damage1, and cataract formation2 are consequences of excessive UV irradiation. As catalase activity has been found to be reduced in cataractuous lenses3, we suggested a protective effect for catalase against UV irradiation. Using blue light of 400 nm, Radimeier proved this in cultures of bovine lens epithelium4,5 (Fig. 1). Showing that UV damage is a result of H2O2 stress. It is important determine whether addition of a 0.36% catalase solution can protect lens epithelial cells against morphological alterations and apoptosis by UV-A also. It remains unknown, whether indirect as well as direct irradiation can cause cell damage.

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References

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© 1998 Springer Science+Business Media Dordrecht

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Mayer, U.M., Klinge, H., Radlmeier, M. (1998). The effects of UV-A light in indirect irradiation on cultures of bovine lens epithelium. In: Coscas, G., Piccolino, F.C. (eds) Retinal Pigment Epithelium and Macular Diseases. Documenta Ophthalmologica Proceedings Series, vol 62. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5137-5_12

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  • DOI: https://doi.org/10.1007/978-94-011-5137-5_12

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6160-5

  • Online ISBN: 978-94-011-5137-5

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