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The Paracoccus Denitrificans Electron Transport System: Aspects of Organisation, Structures and Biogenesis

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Biological Electron Transfer Chains: Genetics, Composition and Mode of Operation

Part of the book series: NATO ASI Series ((ASIC,volume 512))

Abstract

The electron transport system of Paracoccus denitrificans (then known as Micrococcus denitrificans) first attracted significant interest in the 1960’s when it was shown that at least some of its components required for aerobic respiration are similar to those found in mitochondria. The identification of cytochrome c 550 as a protein with significant similarity to mitochondrial cytochrome c led to an early X-ray diffraction structure determination. However, attention was strongly focused on the P. denitrificans electron transfer chain following the publication in 1975 of a review article by John and Whatley [32] that developed the thesis that the aerobic electron transport chain of the organism is more similar to that of the mitochondrion than that found in any other bacterium. The corollary of this thesis was that P. denitrificans is related to an aerobic symbiont from which the present-day mitochondrion is derived [32]. In subsequent years a great deal has been learned about the P. denitrificans electron transport system, much of it confirming at the molecular level that many of its components are indeed closely related to, but often possessing a simpler subunit structure than, those of the mammalian mitochondrion. Furthermore, in the years since 1975 a great deal of insight into other aspects of the electron transport chain has been obtained. This brief review aims to collect together current aspects of this electron transport system. The treatment cannot be comprehensive and does not attempt to relate work with P. denitrificans to that on other bacteria. However, observations on the organism Thiosphaera pantotropha are included.

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  1. Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK

    S. J. Ferguson

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  1. Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands

    G. W. Canters  & E. Vijgenboom  & 

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Ferguson, S.J. (1998). The Paracoccus Denitrificans Electron Transport System: Aspects of Organisation, Structures and Biogenesis. In: Canters, G.W., Vijgenboom, E. (eds) Biological Electron Transfer Chains: Genetics, Composition and Mode of Operation. NATO ASI Series, vol 512. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5133-7_6

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  • DOI: https://doi.org/10.1007/978-94-011-5133-7_6

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