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Dietary Antioxidants and Cardiovascular Disease

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Multiple Risk Factors in Cardiovascular Disease

Part of the book series: Medical Science Symposia Series ((MSSS,volume 12))

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Abstract

There is considerable evidence that oxidation of low density lipoproteins (LDL) plays a crucial step in atherogenesis [1]. There is also evidence that antioxidants help protect LDL from oxidation and can prevent atherosclerosis in animal models [1–3]. A number of observational studies and a few randomized trials have attempted to verify whether antioxidant intake from food and/or supplements may prevent the occurrence of cardiovascular events. Jha et al. recently published an excellent comprehensive overview of the relation of β-carotene, vitamin E, and vitamin C with cardiovascular disease occurrence [4]. In this report, I update the review through a Medline search over the past three years, and add recent studies on flavonoids, another family of antioxidants.

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Authors
  1. Aaron R. Folsom
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Editor information

Editors and Affiliations

  1. Cornell University Medical College, 1300 York Avenue, Room F-105, New York, NY, USA

    Antonio M. Gotto Jr.

  2. National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, USA

    C. Lenfant

  3. Institute of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133, Milan, Italy

    Rodolfo Paoletti  & A. L. Catapano  & 

  4. Giovanni Lorenzini Medical Foundation, Houston, TX, USA

    A. S. Jackson

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© 1998 Springer Science+Business Media Dordrecht

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Folsom, A.R. (1998). Dietary Antioxidants and Cardiovascular Disease. In: Gotto, A.M., Lenfant, C., Paoletti, R., Catapano, A.L., Jackson, A.S. (eds) Multiple Risk Factors in Cardiovascular Disease. Medical Science Symposia Series, vol 12. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5022-4_17

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  • DOI: https://doi.org/10.1007/978-94-011-5022-4_17

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6108-7

  • Online ISBN: 978-94-011-5022-4

  • eBook Packages: Springer Book Archive

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