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Diagnosis, Differential Diagnosis, and Follow-Up of Tumours by Means of FDG PET

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Positron Emission Tomography: A Critical Assessment of Recent Trends

Part of the book series: NATO ASI Series ((ASHT,volume 51))

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Abstract

Ninety-two 18fluoro-deoxy-D-glucose (FDG) PET examinations performed on oncological patients yielded conclusive results for primary diagnostics, staging, restaging and therapeutic monitoring in 39%, 85%, 82% and 93% of the cases, respectively. The 77% overall incidence of conclusive results indicates that the FDG PET technique is a powerful clinical tool. It should be emphasized that this result was attained through careful histopathological investigations, high-resolution anatomic imaging procedures and an active follow-up policy. Additional information was obtained concerning the proliferative capacity of the tumour cells and the extent of the viable tumorous tissue. The metabolically-based determination of the tumour margins by PET and CT-MRI-PET image fusion helped in delineation of the gross tumour volume and its subclinical extent for three-dimensional (3D) radiotherapy planning ensuring a more adequate dose coverage. The value of FDG PET investigations in oncology may be summarized as follows: limited in the primary diagnostics, strong in staging and restaging, very strong in therapeutic monitoring, and investigational in estimations of the proliferative capacity of tumorous tissue and 3D radiation treatment planning.

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Author information

Authors and Affiliations

  1. Department of Radiotherapy, National Institute of Oncology, Budapest, H-1122, Budapest, Ráth György u. 7-9, Hungary

    O. Ésik

  2. Laboratory for Brain Research and PET, The Nobel Institute of Neurophysiology, Karolinska Institute, Stockholm, Sweden

    B. Gulyás

  3. PET Centre, Debrecen University of Medicine, Debrecen, Hungary

    L. Trón

Authors
  1. O. Ésik
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  2. B. Gulyás
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  3. L. Trón
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Editor information

Editors and Affiliations

  1. Department of Neuroscience, Karolinska Institute, Stockholm, Sweden

    Balázs Gulyás

  2. Hungarian PET Foundation, Debrecen, Hungary

    Balázs Gulyás

  3. Institute for Medicine, Forschungszentrum Jülich GmbH, Jülich, Germany

    Hans W. Müller-Gärtner

  4. Department of Nuclear Medicine, Heinrich-Heine-University of Düsseldorf, Düsseldorf, Germany

    Hans W. Müller-Gärtner

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© 1998 Springer Science+Business Media Dordrecht

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Ésik, O., Gulyás, B., Trón, L. (1998). Diagnosis, Differential Diagnosis, and Follow-Up of Tumours by Means of FDG PET. In: Gulyás, B., Müller-Gärtner, H.W. (eds) Positron Emission Tomography: A Critical Assessment of Recent Trends. NATO ASI Series, vol 51. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-4996-9_16

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  • DOI: https://doi.org/10.1007/978-94-011-4996-9_16

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6097-4

  • Online ISBN: 978-94-011-4996-9

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