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The pruritus of cholestasis: behavioral studies shed light on its pathogenesis

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Primary Biliary Cirrhosis

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Abstract

Pruritus is a symptom experienced by 80% of patients with primary biliary cirrhosis (PBC)1 and 20–60% of jaundiced patients2. The presence of pruritus or the degree to which it is experienced does not correlate with routine serum biochemical indices of cholestasis. It can be mild to severe and it does not tend to be easily relieved by scratching.

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Authors
  1. N. V. Bergasa
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  2. E. A. Jones
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Editor information

Editors and Affiliations

  1. Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA

    Keith D. Lindor (Professor of Medicine) (Professor of Medicine)

  2. The Toronto Hospital, Western Division, University of Toronto, 399 Bathurst Street, Wing 4-828, Toronto, ONT, M5T 2S8, Canada

    E. Jenny Heathcote (Professor of Medicine) (Professor of Medicine)

  3. Service d’Hepatologie et Gastroenterologie, AP — Hôpital Saint-Antoine, 184, rue Du Faubourg, Saint-Antoine, 75571, Paris, France

    Raoul Poupon (Professor of Medicine) (Professor of Medicine)

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© 1998 Springer Science+Business Media Dordrecht

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Bergasa, N.V., Jones, E.A. (1998). The pruritus of cholestasis: behavioral studies shed light on its pathogenesis. In: Lindor, K.D., Heathcote, E.J., Poupon, R. (eds) Primary Biliary Cirrhosis. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-4884-9_13

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  • DOI: https://doi.org/10.1007/978-94-011-4884-9_13

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6047-9

  • Online ISBN: 978-94-011-4884-9

  • eBook Packages: Springer Book Archive

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