Abstract
The involvement of leukotrienes (LTs) in asthma mainly concerns the cysteinylleukotrienes (cys-LTs, LTC4, D4 and E4), which are chemical mediators of events in the airways as part of an asthmatic attack1. There is still a debate in the literature whether the proinflammatory compound LTB4, formed from the common unstable epoxide intermediate LTA4, also contributes to the airway inflammation associated with asthma2.
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Kumlin, M. (1998). How to measure leukotrienes in man. In: Rodger, I., Botting, J., Dahlén, SE. (eds) Leukotrienes. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-4880-1_5
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