Selectivity and Protective Activity of Muscarinic Receptor’s Antagonists in Organophosphates Poisoning

Kosmachev, A. B.; Philko, O. A.

doi:10.1007/978-94-011-4641-8_13

A. B. Kosmachev⁸ &
O. A. Philko⁸

Part of the book series: NATO Science Series ((ASDT,volume 25))

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Abstract

The wide use of organophosphorus compounds in industry and home is a certain danger for humans. In this connection the further improvement of the methods to treat organophosphorus poisoning is a significant medical problem. Among many drugs assigned for treatment of organophosphorus intoxication, an important place belongs to muscarinic antagonists (M-antagonists). At the same time, it is necessary to take account of the specific type of muscarinic receptor to be targeted by muscarinic antagonists.

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Authors and Affiliations

Institute of Toxicology Ministry of Health of Russia, Bechterev str. 1, 193019, S. Petersburg, Russia
A. B. Kosmachev & O. A. Philko

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A. B. Kosmachev
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O. A. Philko
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Editors and Affiliations

Department of Studies and Science, German Armed Forces Medical Academy, Munich, Germany
Torsten Sohns & Harald Kempf &
University of Medicine & Pharmacy ”Carol Davila”, Bucharest, Romania
Victor A. Voicu
Department of Studies and Science, Institute of Pharmacology and Toxicology, German Armed Forces Medical Academy, Munich, Germany
Ladislaus Szinicz
Department of Studies and Science, Institute of Microbiology, German Armed Forces Medical Academy, Munich, Germany
Ernst-Juergen Finke
Army Center of Medical Research and University of Medicine and Pharmacy „Carol Davila“, Bucharest, Romania
Constantin Mircioiu
Defence Research Establishment Suffield, Box 4000, Medicine Hat, Alberta, TIB 2 P5, Canada
P. Lundy
An-Ex, Redwood Building, Cf 1 3xF, Cardiff, UK
Keith R. Brain

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Kosmachev, A.B., Philko, O.A. (1999). Selectivity and Protective Activity of Muscarinic Receptor’s Antagonists in Organophosphates Poisoning. In: Sohns, T., et al. NBC Risks Current Capabilities and Future Perspectives for Protection. NATO Science Series, vol 25. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-4641-8_13

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DOI: https://doi.org/10.1007/978-94-011-4641-8_13
Publisher Name: Springer, Dordrecht
Print ISBN: 978-0-7923-5803-9
Online ISBN: 978-94-011-4641-8
eBook Packages: Springer Book Archive

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