Skip to main content

Immunobiological approach to colorectal cancer staging : biological markers, cellular “in situ” immunological response and intranuclear DNA imaging analysis. Old and new parameters. retrospective evaluation and prospective trials after a fifteen year experience

  • Chapter

Summary

The Authors consider whether it is possibile to classify and stage colo-rectal cancer not only on the grounds of its diffusion, histotype and grading, but also on the grounds of its biological expression.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Alderisio M, Ribotta G, Giarnieri E, et al. Aneuploid polyclonality in image analysis: Clinical prognostic value in colorectal cancer. Oncol Rep 1996; 3: 567.

    PubMed  CAS  Google Scholar 

  2. Allison DC, Piantadosi S, Hruban RH, et al. The National Cancer Data Base Report on colon cancer. Cancer 1996; 78: 918.

    Article  Google Scholar 

  3. Aziz D, Peter SB. DNA ploidy and cell cycle analysis: tools for assessment of cancer prognosis. J Clin Lab Anal 1991; 5: 422.

    Article  PubMed  CAS  Google Scholar 

  4. Boring CC, Squireas TS, Tong T, et al. Cancer statistics 1994. Cancer J Clin 1994; 44: 7.

    Article  CAS  Google Scholar 

  5. Bose KK, Allison DC, Hruban RH, et al. A comparison of flow cyrometry and absorption cytometric DNA value as prognostic indicators for pancreatic carcinoma. Cancer 1993; 71: 691.

    Article  PubMed  CAS  Google Scholar 

  6. Braun S, Pantel K. Immunodiagnosis and immunotherapy of isolated tumour cell disseminated to bone marrow of patients with colorectal cancer. Tumori 1995; 81: 78.

    PubMed  CAS  Google Scholar 

  7. Breivik J, Meling GI, Spurkland A, et al. K-Ras mutation in colorectal cancer: relations to patient, age, sex and tomor location. Br J Cancer 1994; 69: 367.

    Article  PubMed  CAS  Google Scholar 

  8. Chang KJ, Enker WE, Melamed M. Influence of tumor cell DNA ploidy on the natural history of rectal cancer. Am J Surg 1987; 153: 184.

    Article  PubMed  CAS  Google Scholar 

  9. Colizza S, Bertolotti A, Di Paola M, et al. The hosth defensive factor grade. Dis Colon Rectum 1978; 22: 93.

    Article  Google Scholar 

  10. Danova M, De Renzis MR, Girino M, et al. DNA content and cell kinetics in colorectal carcinoma. Tumori 1995; 81: 12.

    PubMed  CAS  Google Scholar 

  11. Di Paola M, Midiri G, Amanti C, et al. Concetti di stadiazione dinamica delle neoplasie del colon retto. Min Chir 1989; 44: 75.

    Google Scholar 

  12. Di Paola M, Midiri G, Bertolotti A, et al. Prognostic role of tissue and serum markers. Exp Cl Cancer Res 1989; 8: 102.

    Google Scholar 

  13. Di Paola M, Midiri G, Ramacciato G. Role of monoclonal antibodies in the management of colorectal carcinoma, in Current topics in Surgical Oncology ed. Masson Milano, 1991.

    Google Scholar 

  14. Doerr RJ, Abdel-NABI H, Krag DN, et al. Radiolabeled antibody imaging in the management of colorectal cancer. Ann Surg 1991; 214: 118.

    Article  PubMed  CAS  Google Scholar 

  15. Galassi G, Midiri G, Pastore P, et al. Nuovi orientamenti nella stadiazione delle neoplasie solide. Min Chir 1989; 44: 79.

    CAS  Google Scholar 

  16. Giovagnoli MR, Lukic A, Muraro R, et al. Image cytometry for DNA analysis in endometrial carcinoma correlated with other prognostic parameters. Int J Oncol 1996; 7–809.

    Google Scholar 

  17. Haferkamp O. Inflammatory stromal reaction in well differentiated adenocarcinoma of the large intestine in Metastatic tumor growth, ed. Verlag New York, 1980.

    Google Scholar 

  18. Harlow SP, Eriksen BL, Poggensee L, et al. Prognostic implication of proliferativa activity and DNA aneuploidy in Astler-Coller-Duke’s stage C colonic adenocarcinoma. Cancer Res 1991; 51: 2403.

    PubMed  CAS  Google Scholar 

  19. Jass SR, Loves S, Nothoner SMA. A new prognostic classification for rectal cancer. Lancet 1987; 1: 1303.

    Article  PubMed  CAS  Google Scholar 

  20. Jass SR, Morson BC. Reporting colo-rectal cancer. Clin Pathol 1987; 40: 1016.

    Article  CAS  Google Scholar 

  21. Jessup JM, McGinnis LS, Steele GD, et al. The National Cancer Data Base Report on colon cancer. Cancer 1996; 78: 918.

    Article  PubMed  CAS  Google Scholar 

  22. Midiri G, Amanti C, Benedetti M, et al. CEA tissue staining in colorectal cancer patients. Cancer 1985; 55: 2624.

    Article  PubMed  CAS  Google Scholar 

  23. Midiri G, Amanti C, Consorti F, et al. Usefulness of preoperative CEA levels in the assessment of colorectal cancer patient stage. J Surg Onc 1983; 22: 57.

    Article  Google Scholar 

  24. Midiri G, Amanti C, Consorti F, et al. L’antigene carcinoembrionario CEA come indicatore di radicalità biologica di un intervento chirurgico. Giorn Chir 1988; 9910.

    Google Scholar 

  25. Midiri G, Bertolotti A, Di Paola M, et al. La Stadiazione dinamica in funzione della prognosi delle neoplasie del colon retto. in “ Il ruolo della terapia chirurgica in oncologia” ed. Monduzi Bologna, 1988.

    Google Scholar 

  26. Midiri G, Benedetti M, Campisi C, et al. Tissue CEA detection by immunoperoxidase PAP test in colorectal polyps: correlations with the degree of dysplasia. J Surg Onc 1988; 37: 13.

    Article  Google Scholar 

  27. Midiri G, Bezzi M, Campisi C. La Reazione Immunitaria. in Manuale di Fisiopatologia Chirurgica ed. Masson Milano, 1993.

    Google Scholar 

  28. Midiri G, Di Massimo A, Verrico G, et al. Modelli clinico sperimentali per la definizione di parametri immunologici da integrare ai sistemi di stadiazione tradizionali delle neoplasie colo-rettali. Giorn Chir 1994; 15: 341.

    CAS  Google Scholar 

  29. Midiri G, Tesoriere A, Giarnieri E, et al. Immunità cellulare in situ e valutazione prognostica. Atti xviii Congr. SICO 1:3 Varese 1994.

    Google Scholar 

  30. Midiri G, Tesoriere A, Lombardi A, et al. Cellular in situ immunological response and intranuclear DNA imaging evaluation in colorectal cancer patients. It Rev Med Surg Res 1995; 3: 29.

    Google Scholar 

  31. Midiri G, Giovagnoli MR, Tesoriere A, et al. E’ possibile considerare l’analisi per immagine del DNA intranucleare come un nuovo parametro per la stadiazione del cancro colo-rettale ? Giorn Chir 1998; 19: 9.

    CAS  Google Scholar 

  32. Midiri G, Giarnieri E, Tesoriere A, et al. Is it possible to consider intranuclear DNA imaging as a new parameter for colo-rectal cancer prognostic evaluation ? 1 th World Congr Surg Onc San Diego USA March 1998.

    Google Scholar 

  33. Midiri G, Tesoriere A, Giarnieri E, et al. DNA ploidy and prognosis in colo-rectal cancer patients: preliminary report It J Coloproct 1998 in press.

    Google Scholar 

  34. Moffat FL, Pinsky CM, Hammershaimb L, et al. Clinical utility of external immunoscintigraphy with the IMMU-4 Technetium-99m Fab antibody fragment in patients undergoing surgery for carcinoma of the colon and rectum: results of a pivotal, phase III trial. J CI Onc 1996; 14: 2295.

    Google Scholar 

  35. Orfao A, Ruiz Arguelles A, Lacombe F. Flow citometry in application in haematology. Haematologica 1995; 80: 69.

    PubMed  CAS  Google Scholar 

  36. Pietra N, Sarli L, Sansebastiano G, et al. Prognostic value of ploidy, cell proliferation kinatics and conventional clinicopathologic criteria in patients with colorectal carcinoma. Dis colon cancer 1996; 39: 494.

    CAS  Google Scholar 

  37. Scott N, Cross D, Plumb MI, et al. an investigation of different methods of cell cycle analysis by flow cytometry in rectal cancer. Br J Cancer 1995; 8: 10.

    Google Scholar 

  38. Spandidos DA, Kiaris H, Liondaki E, et al. Activating mutations in the K-Ras gene in ulcerative colitis and Crohn’s disease. Onc Rep 1994; 1: 547.

    CAS  Google Scholar 

  39. Strauli P, Heammerli G. Interaction of locomotive and lytic activities of tumor cells in invasion, in Metastatic tumor growth ed. Verlag New York, 1980.

    Google Scholar 

  40. Vitelli CE, Ramacciato G, Midiri G, et al. Surgical management of recurrent colorectal carcinoma. in “ Current topics in surgical oncology”. Ed. Masson Milano, 1991.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1999 Springer Science+Business Media Dordrecht

About this chapter

Cite this chapter

Midiri, G. et al. (1999). Immunobiological approach to colorectal cancer staging : biological markers, cellular “in situ” immunological response and intranuclear DNA imaging analysis. Old and new parameters. retrospective evaluation and prospective trials after a fifteen year experience. In: Zanella, E. (eds) Advances in Abdominal Surgery. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-4469-8_15

Download citation

  • DOI: https://doi.org/10.1007/978-94-011-4469-8_15

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-5914-5

  • Online ISBN: 978-94-011-4469-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics