Skip to main content

Methods to Assess Baroreflex Sensitivity as a Measure of the Activity of the Autonomic Nervous System

  • Chapter
Advances in Noninvasive Electrocardiographic Monitoring Techniques

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 229))

Abstract

Among the several methods which have been proposed for determination of sympathetic-parasympathetic interactions at the level of the sinus node, the assessment of baroreflex sensitivity (BRS) and the analysis of heart rate variability have been shown to carry prognostic information in ischemic heart disease (1). This article describes several quantitative approaches developed for evaluating BRS including the analysis of reflex responses to pharmacological or mechanical manipulations of baroreceptors, and the analysis of spontaneously occurring changes in blood pressure and heart rate.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. La Rovere MT, Bigger JT Jr, Marcus FI, Mortara A, Schwartz PJ for the ATRAMI Investigators: Baroreflex sensitivity and heart rate variability in prediction of total cardiac mortality after myocardial infarction. Lancet 351: 478–484, 1998

    Article  PubMed  Google Scholar 

  2. Smyth HS, Sleight P, Pickering GW: Reflex regulation of arterial pressure during sleep in man: a quantitative method for assessing baroreflex sensitivity. Circ Res 24: 109–121, 1969

    Article  PubMed  CAS  Google Scholar 

  3. La Rovere MT, Specchia G, Mortara A, Schwartz PJ: Baroreflex sensitivity, clinical correlates and cardiovascular mortality among patients with a first myocardial infarction. A prospective study. Circulation 1988; 78: 816–824

    Article  PubMed  Google Scholar 

  4. Mortara A, La Rovere MT, Pinna GD, Prpa A, Maestri R, Febo O, Pozzoli M, Opasich C, Cobelli F, Tavazzi L: Arterial baroreflex modulation of heart rate in chronic heart failure. Clinical and hemodynamic correlates and prognostic implications. Circulation 96: 3450–3458, 1997

    Article  PubMed  CAS  Google Scholar 

  5. Parati G, Casadei R, Groppelli A, Di Rienzo M, Mancia G: Comparison of finger and intra-arterial blood pressure monitoring at rest and during laboratory testing. Hypertension 13: 647–655, 1989

    Article  PubMed  CAS  Google Scholar 

  6. Bristow JD, Honour AJ, Pickering GW, Sleight P, Smyth HS: Diminished baroreflex sensitivity in high blood pressure. Circulation 1969; 39: 48–54

    Article  PubMed  CAS  Google Scholar 

  7. Eckberg DL, Drabinsky M, Braunwald E: Defective cardiac parasympathetic control in patients with heart disease. N Engl J Med 285: 877–883, 1971

    Article  PubMed  CAS  Google Scholar 

  8. Osculati G, Grassi G, Giannattasio C, Seravalle G, Valagussa F, Zanchetti A, Mancia G: Early alterations of the baroreceptor control of heart rate in patients with acute myocardial infarction. Circulation 81: 939–948, 1990

    Article  PubMed  CAS  Google Scholar 

  9. Sleight P, La Rovere MT, Mortara A, Maestri R, Leuzzi S, Bianchini B, Tavazzi L, Bernardi L: Physiology and physiopathology of heart rate and blood pressure variability in humans: is power spectral analysis largely an index of baroreflex gain? Clinical Science 1995; 88: 103–109

    PubMed  CAS  Google Scholar 

  10. Bernardi L, Bianchini B, Spadacini G, Leuzzi S, Valle F, Marchesi E, Passino C, Calciati A, Vigano’ M, Rinaldi M, Martinelli L, Finardi G, Sleight P: Demonstrable cardiac reinnervation after human heart transplantation by carotid baroreflex modulation of RR interval. Circulation 1995; 92: 2895–2903

    Article  PubMed  CAS  Google Scholar 

  11. Parati G, Di Rienzo M, Bertinieri G, Pomidossi G, Casadei R, Groppelli A, Pedotti A, Zanchetti A, Mancia G: Evaluation of the baroreceptor-heart rate reflex by 24-hour intra-arterial blood pressure monitoring in humans. Hypertension 12: 214–222, 1988

    Article  PubMed  CAS  Google Scholar 

  12. Robbe HWJ, Mulder LJM, Ruddel H, Langewitz WA, Veldman JBB, Mulder G: Assessment of baroreceptor reflex sensitivity by means of spectral analysis. Hypertension 10: 538–543, 1987

    Article  PubMed  CAS  Google Scholar 

  13. Pagani M, Somers V, Furlan R, Dell’Orto S, Conway J, Cerutti S, Sleight P, Malliani A: Changes in autonomic regulation induced by physical training in mild hypertension. Hypertension 12: 600–610, 1988

    Article  PubMed  CAS  Google Scholar 

  14. Maestri R, Pinna GD, Mortara A, La Rovere MT, Tavazzi L: Assessing baroreflex sensitivity in post-myocardial infarction patients: comparison of spectral and phenylephrine techniques. J Am Coll Cardiol 31: 344–351, 1998

    Article  PubMed  CAS  Google Scholar 

  15. Pitzalis MV, Mastropasqua F, Passantino A, Massari F, Ligurgo L, Forleo C, Balducci C, Lombardi F, Rizzon P: Comparison between noninvasive indices of baroreceptor sensitivity and the phenylephrine method in post-myocardial infarction patients. Circulation 97: 1362–1367, 1998

    Article  PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2000 Springer Science+Business Media Dordrecht

About this chapter

Cite this chapter

La Rovere, M.T. (2000). Methods to Assess Baroreflex Sensitivity as a Measure of the Activity of the Autonomic Nervous System. In: Osterhues, HH., Hombach, V., Moss, A.J. (eds) Advances in Noninvasive Electrocardiographic Monitoring Techniques. Developments in Cardiovascular Medicine, vol 229. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-4090-4_5

Download citation

  • DOI: https://doi.org/10.1007/978-94-011-4090-4_5

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-5796-7

  • Online ISBN: 978-94-011-4090-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics