Purines and the control of renal function

  • T. W. Stone
  • H. A. Simmonds


The manner in which the kidney controls the level of purine end-products circulating in body-fluids has been described in Chapter 4. In this chapter we will examine the reverse process: the current concepts relating to the putative role of purines in the control of renal function, specifically adenosine and — through the GTP-binding regulatory protein — cyclic AMP.


Proximal Tubule Renal Blood Flow Renin Release Renin Secretion Extracellular Adenosine 
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Copyright information

© Springer Science+Business Media Dordrecht 1991

Authors and Affiliations

  • T. W. Stone
    • 1
  • H. A. Simmonds
    • 2
  1. 1.Department of PharmacologyThe UniversityGlasgowUK
  2. 2.Purine Research LaboratoryUnited Medical and Dental School of Guy’s and St. Thomas’ HospitalsLondonUK

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