Skip to main content

An Investigation on the Penetration of Lipids in the Bilayer of Stratum Corneum

  • Chapter
The Structure, Dynamics and Equilibrium Properties of Colloidal Systems

Part of the book series: NATO ASI Series ((ASIC,volume 324))

  • 458 Accesses

Abstract

A simplified mixture of model stratum corneum was analyzed to make an estimation on the penetration of lipids on the stratum corneum lipid structure. Small x-ray diffractometry and optical microscopy were employed for these purposes.

The small angle x-ray diffractograms showed the lipids to be partitioned in the hydrated acid/soap host layered structure between the methyl group layers. Cholesterol, however, which was entirely located in the acid/soap chains, attracted other compounds from the location between the methyl group layers.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 259.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 329.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. A.M. Kligman, The Epidermis. (W. Montagna, Ed.), Academic Press: New York-London, Chapter 20 (1964).

    Google Scholar 

  2. P.M. Elias and D.S. Friend, J. Cell. Biol. 65, 185 (1975).

    Article  Google Scholar 

  3. G.E. Burch and P. Wisnor, Arch. Internal. Med. 74, 437 (1944).

    Article  Google Scholar 

  4. P.M. Elias, N.S. McNutt and D.S. Friend. Anat. Rec. 189, 577.

    Google Scholar 

  5. W.P. Smith, M.S. Christenson, S. Nachet and E.H. Gans, J. Invest. Dermatol, 78, 7 (1982).

    Article  CAS  Google Scholar 

  6. P.M. Elias, J. Goerke and D.S. Friend, J. Invest. Dermatol. 68, 535, (1977).

    Article  Google Scholar 

  7. G.M. Gray and R.J. White, Ibid 70, 336 (1978).

    CAS  Google Scholar 

  8. G.M. Gray and H.J. Yardley, J. Lipid Research 16, 435 (1975).

    Google Scholar 

  9. E.G. Bligh and W.J. Dyer, Can. J. Biochem. Physiol.

    Google Scholar 

  10. W. Abraham, P.W. Wertz and D.T. Downing, J. Lipid Research 26, 761 (1985).

    CAS  Google Scholar 

  11. A.W. Ranasinghe, P.W. Wertz, D.T. Downing and J.C. Mackenzie, J. Invest. Dermatol. 86, 187 (1986).

    Article  CAS  Google Scholar 

  12. P.M. Elias, Ibid 80, 44 (1983).

    CAS  Google Scholar 

  13. P.M. Elias, J. Dermatol. 20, 1 (1981).

    CAS  Google Scholar 

  14. G.K. Menon, S. Grayson and P.M. Elias, J. Invest. Dermatol. 84, 508 (1985).

    Article  CAS  Google Scholar 

  15. P.W. Wertz, W. Abraham, L. Landmann and D.T. Downing, J. Invest. Dermatol. 87, 582 (1986).

    Article  CAS  Google Scholar 

  16. W. Abraham, P.M. Wertz, L. Landmann and D.T. Downing, J. Lipid Research 26, 761 (1985).

    CAS  Google Scholar 

  17. P.M. Elias and D.S. Friend, J. Cell Biol. 65, 501 (1975).

    Article  CAS  Google Scholar 

  18. P. Ekwall, Advances in Liquid Crystals. (G.H. Brown. Ed.), Academic Press: New York (1975) p. 1.

    Google Scholar 

  19. S.E. Friberg and D.W. Osborne, J. Disp. Sci. & Techn. 6(4), 485 (1985).

    Article  CAS  Google Scholar 

  20. F.B. Rosevear, J. Am. Oil Chem. Soc. 31, 628 (1954).

    Article  CAS  Google Scholar 

  21. S.E. Friberg and L.B. Goldsmith, Unpublished results.

    Google Scholar 

  22. Biological Membranes (D. Chapman, Ed.), Academic Press: New York, (1968).

    Google Scholar 

  23. B.P. Schoenborn, Chem. Eng. News 55, 31 (1977).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1990 Springer Science+Business Media Dordrecht

About this chapter

Cite this chapter

Suhaimi, H., Friberg, S.E. (1990). An Investigation on the Penetration of Lipids in the Bilayer of Stratum Corneum. In: Bloor, D.M., Wyn-Jones, E. (eds) The Structure, Dynamics and Equilibrium Properties of Colloidal Systems. NATO ASI Series, vol 324. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-3746-1_33

Download citation

  • DOI: https://doi.org/10.1007/978-94-011-3746-1_33

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-5666-3

  • Online ISBN: 978-94-011-3746-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics