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Separation Techniques with Porous Glass Membranes: A Comparison of Dextrane and Protein Separations

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Abstract

Porous glass hollow fibre membranes can be used for the separation of molecular mixtures as well as in microfiltration. In both cases, the degree of retention of a certain particle is mainly determined by the pore size of the membrane; the particular chemical surface modification of the membrane will have an additional influence. In this work, mixtures of dextranes have been used to evaluate the separation capacity of porous glass membranes. Interesting effects can be observed when higher molecular weight dextranes are used. A possible explanation is the flexibility of such large molecules and their deformation in a fluid flow field. Modelling transport through a membrane as a motion of a sphere (the diameter of which is the Stokes’ diameter) through a cylindrical pore, the retention of dextranes and of proteins can be described by the same theory.

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References

  1. Hood, H. P. and Nordberg, M. E., U.S. Patent #2,106,744, Feb. 1, 1938

    Google Scholar 

  2. Schnabel, R. and Langer, P. (1989),’Structural and chemical properties of glass capillary membranes and their use in protein separation’, Glastech. Ber. 62, 56–62

    CAS  Google Scholar 

  3. Langer, P., Eichhorn, U. and Schnabel, R. (1990),’Bioran porous glass membranes for solvent purification’, Proc. 5th World Filtration Congress, Nice, 134–138

    Google Scholar 

  4. Unger, K.K.,’Porous Silica’, Elsevier, Amsterdam 1979

    Google Scholar 

  5. Chang, S. H., Gooding, K. M. and Regnier, F. E. (1976), J. Chromatogr. 125, 103.

    Article  CAS  Google Scholar 

  6. Messing, R. A. (ed.),’Immobilized Enzymes for Industrial Reactors’, Academic Press, New York 1975

    Google Scholar 

  7. Langer, P. and Schnabel, R. (1990),’Separation with porous glass membranes and controlled pore glass (CPG) chromatography’, Separations for Biotechnology Vol. 2, Ed. D. L. Pyle, Elsevier, London, 371–380

    Google Scholar 

  8. Schnabel, R., Langer, P. and Breitenbach, S. (1988),’Separation of Protein mixtures by Bioran porous glass membranes’, J. Mem. Sci. 36, 55–66

    Article  CAS  Google Scholar 

  9. Langer, P., Breitenbach, S. and Schnabel, R. (1989),’Ultrafiltration with porous glass membranes’, Proc. Int. Techn. Conf. on Membrane Separation Processes, Brighton, 105–119

    Google Scholar 

  10. Gekas, V. (ed.),’Terminology for pressure driven membrane operations’, Lund 1986

    Google Scholar 

  11. de Balmann, Hélène and Nobrega, Ronaldo (1989),’The deformation of dextrane molecules. Causes and consequences in ultrafiltration’, J. Mem. Sci. 40, 311–327

    Article  Google Scholar 

  12. Granath, K. A. and Kvist, B. E. (1967),’Molecular weight distribution analysis by gel chromatography on Sephadex’, J. Chromatogr. 28, 69–81s

    Article  CAS  Google Scholar 

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© 1991 Elsevier Science Publishers Ltd, England

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Langer, P., Breitenbach, S., Schnabel, R. (1991). Separation Techniques with Porous Glass Membranes: A Comparison of Dextrane and Protein Separations. In: Turner, M.K. (eds) Effective Industrial Membrane Processes: Benefits and Opportunities. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-3682-2_19

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  • DOI: https://doi.org/10.1007/978-94-011-3682-2_19

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-1-85166-723-9

  • Online ISBN: 978-94-011-3682-2

  • eBook Packages: Springer Book Archive

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