Skip to main content

Production of important phytochemicals through plant cell cultures and scale-up operations: Limitations and prospects

  • Chapter
Horticulture — New Technologies and Applications

Part of the book series: Current Plant Science and Biotechnology in Agriculture ((PSBA,volume 12))

Abstract

The human population depends on plants, not only for its staple foods, but also for various chemicals derived from them. The phytochemicals of importance may be drugs, food additives, and a range of other chemicals needed for various end uses. The developments in modern biology have made it possible to exploit the productivity of plants in a desired manner, and also to modify then suitably. Despite the progress made in chemical synthesis, we still depend upon plant sources for a number of compounds, either because of complexities in chemical synthesis or because of their assured safety and in some cases for economic considerations. Moreover, due to the enormous population explosion the emphasis has been laid on increasing staple food crops, as a result land available for cultivation of plants for phytochemicals is diminishing. In the above context, it is relevant to develop alternative methods of production of phytochemicals by cell culture technology.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • DiCosmo, F. and Misawa, M. (1985) Eliciting secondary metabolism in plant cell cultures. Trends Biotechnol. 3: 318–322.

    Article  CAS  Google Scholar 

  • Eden, L. and Van der, D.H. (1985) Microbial synthesis of the sweet tasting plant protein thaumatin, Trends Biotechnol. 3: 61–64.

    Article  Google Scholar 

  • Fujita, Y., Hara, Y., Suga, C. and Morimoto, T. (1981) Production of shikonin derivative by cell suspension cultures of Lithospermum erythrorhizon II. A new medium for the production of shikonin derivatives. Plant Cell Rep. 1: 61–63.

    Article  CAS  Google Scholar 

  • Kreis, W. and Reinhard, E. (1988) 12 β-Hydroxylation of Digitoxin by suspension-cultured Digitalis lanata cells. Production of deacetyllanatoside C using a two stage culture method. Planta Medica 2: 95–110.

    Google Scholar 

  • Kutchan, T.M. Hampp, N, Lottspeich, F. Beyreuther, K. and Zenk, M.H. (1988) The cDNA clone for strictosidine synthase from Rauwolfia serpentina. FEBS letters 2370: 40–44.

    Article  Google Scholar 

  • Martin, S.M. (1980) Mass systems for plant cell suspension. In: Staba, E.J. ed. Plant tissue culture as a source of biochemicals, pp. 149–166. CRC Press Inc., Boca Raton.

    Google Scholar 

  • Noguchi, M., Matsumoto, T., Hirata, Y., Yamamoto, K., Katsuyama, A., Kato, A.S., Azechi, S. and Kato, K. (1977) Improvement of growth rate of plant cell cultures. In: Barz, W., Reinhard, E. and Zenk, M.H. eds. Plant tissue culture and its biotechnological application, pp. 85–94. Springer-Verlag, Berlin.

    Chapter  Google Scholar 

  • Rajasekaran, T., Rajendran, L., Ravishankar, G.A. and Venkataraman, L.V. (1991) Influence of nutrient stress on pyrethrin production in cultured cells of pyrethrum (Chyysanthemum cinerariaefolium), Current Science (In press).

    Google Scholar 

  • Ravishankar, G.A. and Grewal, S. (1990) ATPase activity as an index of growth capability of cultured cells of Dioscorea and Physochlaina. Biochem. Intl. 20: 897–901.

    CAS  Google Scholar 

  • Ravishankar, G.A., Rajesekaran, T., Sarma, K.S. and Venkataraman, L.V. (1989) Production of pyrethrins in cultured tissues of pyrethrum (Chrysanthemum cinerariaefolium vis) Pyrethrum Post 17: 66–69.

    CAS  Google Scholar 

  • Ravishankar, G.A., Sarma, K.S., Venkataraman, L.V. and Kadyan, A.K. (1988) Effect of nutritional stress on capasaicin production in immobilized cell cultures of Capsicum annuum. Current Science 57: 381–383.

    CAS  Google Scholar 

  • Sasse, F., Knobloch, K.H. and Berlin, J. (1982) Induction of secondary metabolism in cell suspension cultures of Catharanthus roseus, Nicotiana tabacum and Peganum harmala. In: Fujiwara A. ed. Plant issue culture, 1982 pp. 343–344, Japanese Association for Plant Tissue culture, Japan.

    Google Scholar 

  • Sudhakar Johnson, T. Ravishankar, G.A. and Venkataraman, L.V. (1990) In vitro capsaicin production by immobilized cells and placental tissues of Capsicum annuum L. grown in liquid medium, Plant Science 70: 223–229.

    Article  Google Scholar 

  • Visvanath, S., Ravishankar, G.A. and Venkataraman, L.V. (1990) Induction of crocin, crocetin, picrocrocin and safranal synthesis in callus cultures of saffron- Crocus sativus L. Biotechnol. Appl. Biochem. 12: 336–340.

    CAS  Google Scholar 

  • Vollosovitch, A.G. (1988) Some peculiarities of alkaloid accumulation in tissue culture Rauwolfia serpentina Benth. 14. Int. Congress of Biochemistry, Prag, Abstract WE: C. 29–5.

    Google Scholar 

  • Zenk, M.H. (1990) Plant cell cultures: a potential in food and bio-technology. Food Biotechnol. 4: 461–470.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1991 Springer Science+Business Media Dordrecht

About this chapter

Cite this chapter

Ravishankar, G.A., Venkataraman, L.V. (1991). Production of important phytochemicals through plant cell cultures and scale-up operations: Limitations and prospects. In: Prakash, J., Pierik, R.L.M. (eds) Horticulture — New Technologies and Applications. Current Plant Science and Biotechnology in Agriculture, vol 12. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-3176-6_39

Download citation

  • DOI: https://doi.org/10.1007/978-94-011-3176-6_39

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-5401-0

  • Online ISBN: 978-94-011-3176-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics