Abstract
On the basis of a number of animal experiments with implantation of metals, ceramics, composits, mainly into the distal femur of rabbits, some insight could be collected on the tissue response, the materials response and the biomechanical guality of the implant/tissue bond. Some principles for the anchoring of implants to bone were demonstrated.
Additionally, surgically and by post-mortem examination retrieved implants and the surrounding tissue were analysed for structure and quality. Furthermore, in a limited number of cases the metal content in the soft tissue layer was chemically determined. In some cases there was a rather high content of metals in the soft tissue layer. The high metal concentration seems to be not compatible with normal live of cells occurring in the imflammatory and reparatory or regenerative product.
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© 1992 Elsevier Science Publishers Ltd
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Gross, U., Müller-Mai, C., Voigt, C. (1992). Systemic Control of Tissue and Cell Reactions Relating to Ceramic Implants. In: Ravaglioli, A., Krajewski, A. (eds) Bioceramics and the Human Body. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-2896-4_38
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DOI: https://doi.org/10.1007/978-94-011-2896-4_38
Publisher Name: Springer, Dordrecht
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