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Resistance ’91: Achievements and Developments in Combating Pesticide Resistance pp 218–227Cite as

Mechanisms of Resistance to Fungicides

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Abstract

Fungicide resistance is a problem which followed the development of antifungals with specific biochemical modes of action. It is not surprising that the primary mechanism of resistance to these new specific fungicides is target site based. The most characterized example of fungicide resistance based on a modified target is resistance to the benzimidazole class of fungicides such as carbendazim. Several laboratory studies have clearly shown by genetic and biochemical analysis that modified tubulin is the mechanism of benzimidazole resistance. Resistance mechanisms to compounds such as the phenylamides, carboxamides, polyoxins, and sterol biosynthesis inhibitors have been investigated and will be discussed to exemplify the diversity of mechanisms used by fungi to circumvent the toxicity of modern disease control agents.

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Author information

Authors and Affiliations

  1. DowElanco Research Laboratories, 2001 W. Main St., Greenfield, Indiana, USA, 46140

    M. J. Henry

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  1. M. J. Henry
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Editors and Affiliations

  1. Rothamsted Experimental Station, Harpenden, Herts, UK

    Ian Denholm  & Alan L. Devonshire  & 

  2. Long Ashton Experimental Station, Bristol, UK

    Derek W. Hollomon

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© 1992 SCI

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Henry, M.J. (1992). Mechanisms of Resistance to Fungicides. In: Denholm, I., Devonshire, A.L., Hollomon, D.W. (eds) Resistance ’91: Achievements and Developments in Combating Pesticide Resistance. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-2862-9_18

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  • DOI: https://doi.org/10.1007/978-94-011-2862-9_18

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-1-85166-886-1

  • Online ISBN: 978-94-011-2862-9

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