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Part of the book series: NATO ASI Series ((ASID,volume 68))

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Abstract

This chapter summarizes the panel discussion on the use of brain imaging to study behavioral functions and presents recommendations for future research in this area. The first part of the discussion focused on arousal-related neural systems mediating non-specific effects that are common in behavioral activation. It was suggested that non-specific activity changes related to arousal effects could be identified and separated from specific effects in 2-DG experiments in various ways. The ability to separate these effects depends on the control conditions in the particular experiment and the relationship of the results to common changes found in other studies with arousing effects, e.g., presentation of an aversive and rewarding stimuli. The second part dealt with technical considerations in the quantification of autoradiographs focused on the use of pseudo-color scales versus densitometric profiles, determination of the regions of interest for analysis, choice of film and processing factors for autoradiography and the use of perfusion. The discussion concluded with the role of statistics in 2-DG evaluations. Although adequate statistical analyses are necessary in most studies, it was noted that classical statistical techniques may not be suited for 2-DG data.

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References

  • Amsel, A., Dept. of Psychology and Institute for Neuroscience, University of Texas, Austin, TX 78712, USA. — Brown, L.L., Dept. Neuroscience, Albert Einstein College of Medicine, Bldg. K Rm. 601, 1300 Morris Park Ave., Bronx, NY 104161, USA. — Caldecott-Hazard, S., Center for Psychiatry, Florida Hospital, Orlando, FL 32803, USA. — Cassone, V., Department of Biology, Texas A&M University, College Station, TX 778.:13, USA. — Crews, D.P., Institute of Reproductive Biology, Departments of Zoology and Psychology, University of Texas, Austin, TX 78712, USA. — Finkenstädt, Th., Schering AG, 1000 Berlin 65, Germany. — Fox, P.T., Research Imaging Center, University of Texas Health Sci.Ctr., 7703 Floyd Curl Drive, San Antonio, TX 78284, USA. — Gonzalez-Lima, F., Dept. of Psychology and Institute for Neuroscience, University of Texas, Austin, TX 78712, USA. Homitz, B., Laboratory of Neurosciences, National Institute of Aging, National Institutes of Health, Bldg. 10 Rm. 6C414, Bethesda. MD 20892, USA. — Nobrega, J.N., Neuroimaging Research Section, Clarke Institute of Psychiatry. 250 College Street, Toronto, Ontario M5T 1R8, Canada. — Rose, S.P., Biology Department, The Open University, Walton Hall, Milton Keynes, MK7 6AA, UK — Scheich, H., Institute for Zoology, Technical University Darmstadt, Schnittspahnstr. 3, D-6100 Darmstadt, Germany. — Sharp, F.R, Department of Neurology, University of California at San Francisco, Veterans Administration Medical Center, 4150 Clement Street, San Francisco, CA 9.:1121, USA. — Sokoloff, L., National Institute of Mental Health, Laboratory of Cerebral Metabolism, Building 36 Room 1A-05, Bethesda, MD 20892, USA.

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© 1992 Kluwer Academic Publishers

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Finkenstädt, T., Gonzalez-Lima, F., Mcintosh, A.R. (1992). Discussions on Brain Imaging of Behavioral Functions. In: Gonzalez-Lima, F., Finkenstädt, T., Scheich, H. (eds) Advances in Metabolic Mapping Techniques for Brain Imaging of Behavioral and Learning Functions. NATO ASI Series, vol 68. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-2712-7_19

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  • DOI: https://doi.org/10.1007/978-94-011-2712-7_19

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-0-7923-1947-4

  • Online ISBN: 978-94-011-2712-7

  • eBook Packages: Springer Book Archive

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