Abstract
Autonomic imbalance, through differential effects of catecholamines, has long been hypothesized as a major mechanism leading to a number of clinical disorders, particularly those involving the heart [1]. The largest source of catecholamines is found in the sympathetic nerves of the heart, which are distributed on a regional basis [2]. Only in the past few years has it been possible to evaluate abnormalities in heart innervation in the intact animal. Recent developments in cardiac imaging have led to the ability to map the distribution of the sympathetic nerves in vivo. As a result, the pathophysiologic mechanisms relating alterations in sympathetic nerve activity to disease processes are now being explored.
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© 1992 Springer Science+Business Media Dordrecht
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Dae, M.W. (1992). Scintigraphic assessment of cardiac innervation using iodine-123 metaiodobenzylguanidine. In: van der Wall, E.E., Sochor, H., Righetti, A., Niemeyer, M.G. (eds) What’s New in Cardiac Imaging?. Developments in Cardiovascular Medicine, vol 133. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-2456-0_28
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DOI: https://doi.org/10.1007/978-94-011-2456-0_28
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