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Molecular biology of herpes simplex virus

  • Chapter
Molecular and Cell Biology of Sexually Transmitted Diseases

Part of the book series: Molecular and Cell Biology of Human Diseases Series ((Mol. Cell Biol. Hu. Dis.))

  • 109 Accesses

Abstract

Herpes . . . in the current post sexual-revolution era is certainly a familiar term yet the virus responsible is truly ancient. Indeed, herpes simplex virus has been with us for far longer than we have been Homo sapiens. Although oral cold sores were described by 100 AD (Wildy, 1973) and genital herpes was recognized as a sexually transmissible disease in the early eighteenth century (Astruc, 1736; Diday and Doyon, 1886) it was not until 1962 that two serologically distinct herpes simplex viruses were recognized; HSV-1 (primarily oral-labial) and HSV-2 (primarily genital) (Schnewiess, 1962; Nahmais and Dowdle, 1968). Detailed knowledge of HSV has emerged largely in the last 20 years, but it is accumulating at an accelerating pace in parallel with the sophistication of molecular biology.

And nature must obey necessity Shakespeare, Julius Caesar, IV, iii

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Authors
  1. David E. Barker
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  2. Bernard Roizman
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  3. Marjorie B. Kovler
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  1. Charing Cross and Westminster Medical School, London, UK

    David Wright  & Leonard Archard  & 

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Barker, D.E., Roizman, B., Kovler, M.B. (1992). Molecular biology of herpes simplex virus. In: Wright, D., Archard, L. (eds) Molecular and Cell Biology of Sexually Transmitted Diseases. Molecular and Cell Biology of Human Diseases Series. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-2384-6_9

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  • DOI: https://doi.org/10.1007/978-94-011-2384-6_9

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