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Cell adhesion and the basement membrane in early epidermal morphogenesis

  • Chapter
Epithelial Organization and Development

Abstract

The primary processes of vertebrate development include cell division, differentiation and morphogenesis (Edelman, 1988). Morphogenesis can be further divided into the processes of adhesion, and migration, which are controlled by adhesion components (receptors, ligands/ co-receptors and associated cytoskeletal components). We are investigating the molecular mechanisms by which morphogenesis is manifest in stratifying epidermis. Emphasis is placed on the basal and suprabasal cell populations and the integrin class of adhesion receptors. We believe that the integrin receptors regulate functions in these epidermal cells that are common to epithelium in general.

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  1. Fred Hutchinson Cancer Research Center and the Department of Pathobiology, University of Washington, USA

    William G. Carter, Banu E. Symington & Pritinder Kaur

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  1. William G. Carter
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  2. Banu E. Symington
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  3. Pritinder Kaur
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  1. Department of Biology, School of Biological Sciences, University of Southampton, Bassett Crescent East, Southampton, SO9 3TU, UK

    Tom P. Fleming

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© 1992 Springer Science+Business Media Dordrecht

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Carter, W.G., Symington, B.E., Kaur, P. (1992). Cell adhesion and the basement membrane in early epidermal morphogenesis. In: Fleming, T.P. (eds) Epithelial Organization and Development. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-2354-9_11

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  • DOI: https://doi.org/10.1007/978-94-011-2354-9_11

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-5040-1

  • Online ISBN: 978-94-011-2354-9

  • eBook Packages: Springer Book Archive

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