Skip to main content

Environmental perturbations of oxygen transport in teleost fishes: causes, consequences and compensations

  • Chapter
Fish Ecophysiology

Part of the book series: Chapman & Hall Fish and Fisheries Series ((FIFI,volume 9))

Abstract

Aquatic environments exhibit large spatial and temporal variations in physico- chemical factors that influence the physiology of fishes. Environmental changes in O2 and CO2 tensions, temperature, salinity, acidity, and input of toxic substances can be of both man-made and natural origin. Oxygen-depleted waters, for instance, occur naturally in habitats with heavy degradation of organic matter. Anthropogenic activity has expanded the number of environments with ‘extreme conditions’, and has created new environmental problems. Periodic or chronic oxygen depletion resulting from eutrophication is now a well-known phenomenon in many freshwater and coastal areas. Combustion of fossil fuels (emitting nitrogen and sulphur oxides) has acidified many freshwater ecosystems. Furthermore industrial activity has increasingly contaminated waters with toxic substances.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Albers, C, Goetz, K.-H. and Hughes, G.M. (1983) Effect of acclimation temperature on intraerythrocytic acid-base balance and nucleoside triphosphates in the carp, Cyprinus carpio. Respir. Physiol, 54, 145–59.

    Article  PubMed  CAS  Google Scholar 

  • Bath, R.N. and Eddy, F.B. (1979) Ionic and respiratory regulation in rainbow trout during rapid transfer to seawater. J. comp. Physiol, 134, 351–7.

    CAS  Google Scholar 

  • Booth, J.H. (1979) The effects of oxygen supply, epinephrine, and acetylcholine on the distribution of blood flow in trout gills. J. exp. Biol, 83, 31–9.

    CAS  Google Scholar 

  • Borgese, F., Garcia-Romeu, F. and Motais, R. (1987) Ion movements and volume changes induced by catecholamines in erythrocytes of rainbow trout: effect of pH. J. Physiol, Lond., 382, 145–57.

    PubMed  CAS  Google Scholar 

  • Cameron, J.N. (1970) The influence of environmental variables on the hematology of pinfish (Lagodon rhomboides) and striped mullet (Mugil cephalus). Comp. Biochem. Physiol, 32, 175–92.

    Article  PubMed  CAS  Google Scholar 

  • Cossins, A.R. and Kilbey, R.V. (1989) The seasonal modulation of Na+/H+ exchanger activity in trout erythrocytes. J. exp. Biol, 144, 463–78.

    Google Scholar 

  • Dejours, P. (1973) Problems of control of breathing in fishes, in Comparative Physiology (eds L. Bolis, K. Schmidt-Nielsen and S.H.P. Maddrell), North-Holland/American Elsevier, Amsterdam, pp. 117–33.

    Google Scholar 

  • Dejours, P. (1975) Principles of Comparative Respiratory Physiology, North-Holland/American Elsevier, Amsterdam, 254 pp.

    Google Scholar 

  • De Wilde, M.A. and Houston, A.H. (1967) Hematological aspects of the thermoacclimatory process in the rainbow trout, Salmo gairdneri. J. Fish. Res. Bd Can., 24, 2267–81.

    Article  Google Scholar 

  • Dobson, G.P. and Baldwin, J. (1982) Regulation of blood oxygen affinity in the Australian blackfish Gadopsis marmoratus. II. Thermal acclimation. J. exp. Biol, 99, 245–54.

    CAS  Google Scholar 

  • Eddy, F.B. and Williams, E.M. (1987) Nitrite and freshwater fish. Chem. Ecol, 3, 1–38.

    Article  CAS  Google Scholar 

  • Fievet, B. and Motais, R. (1991) Na+/H+ exchanges and red cell functions in fish, in Advances in Comparative and Environmental Physiology, Vol. 8 (ed. R. Gilles). Springer-Verlag, Berlin, pp. 79–104.

    Google Scholar 

  • Fievet, B., Motais, R. and Thomas, S. (1987) Role of adrenergic-dependent H+ release from red cells in acidosis induced by hypoxia in trout. Am.J. Physiol, 252, R269–75.

    PubMed  CAS  Google Scholar 

  • Fonselius, S. (1981) Oxygen and hydrogen sulphide conditions in the Baltic Sea. Mar. Poll Bull, 12, 187–94.

    Article  CAS  Google Scholar 

  • Fritsche, R. and Nilsson, S. (1993) Cardiovascular and ventilatory control during hypoxia, in Fish Ecophysiology (eds J.C. Rankin and F.B. Jensen), Chapman and Hall, London, pp. 180–206.

    Google Scholar 

  • Glass, M.X., Andersen, N.A., Kruhoffer, M., Williams, E.M. and Heisler, N. (1990) Combined effects of environmental PO 2 and temperature on ventilation and blood gases in the carp Cyprinus carpio L. J. exp. Biol, 148, 1–17.

    Google Scholar 

  • Graham, M.S. and Fletcher, G.L. (1986) High concentrations of methemoglobin in five species of temperate marine teleosts. J. exp. Zool, 239, 139–42.

    Article  PubMed  CAS  Google Scholar 

  • Härdig, J. and Hoglund, L.B. (1984) Seasonal variations in blood components of reared Baltic salmon, Salmo salar L. J. Fish Biol, 24, 565–79.

    Article  Google Scholar 

  • Hardig, J., Olsson, L.A. and Hoglund, L.B. (1978) Autoradiography on erythrokinesis and multihemoglobins in juvenile Salmo salar L. at various respiratory gas regimes. Actaphysiol. scand., 103, 240–51.

    Article  CAS  Google Scholar 

  • Heath, A.G. and Hughes, G.M. (1973) Cardiovascular and respiratory changes during heat stress in rainbow trout (Salmo gairdneri). J. exp. Biol, 59, 323–38.

    PubMed  CAS  Google Scholar 

  • Heisler, N. (1986) Acid-base regulation in fishes, in Acid-Base Regulation in Animals (ed. N. Heisler), Elsevier, Amsterdam, pp. 309–56.

    Google Scholar 

  • Hochachka, P. and Somero, G.N. (1973) Strategies in Biochemical Adaptation, Saunders, Philadelphia, 358 pp.

    Google Scholar 

  • Holeton, G.F. and Randall, D.J. (1967) The effect of hypoxia upon the partial pressure of gases in the blood and water afferent and efferent to the gills of rainbow trout. J. exp. Biol, 46, 317–27.

    PubMed  CAS  Google Scholar 

  • Holmgren, S. and Nilsson, S. (1975) Effects of some adrenergic and cholinergic drugs on isolated spleen strips from the cod, Gadus morhua. Eur. J. Pharmacol., 32, 163–69.

    Article  PubMed  CAS  Google Scholar 

  • Houston, A.H. and Koss, T.F. (1984) Erythrocytic haemoglobin, magnesium and nucleoside triphosphate levels in rainbow trout exposed to progressive heat stress. J. therm. Biol, 9, 159–64.

    Article  CAS  Google Scholar 

  • Houston, A.H. and Smeda, J.S. (1979) Thermoacclimatory changes in the ionic microenvironment of haemoglobin in the stenothermal rainbow trout (Salmo gairdneri) and eurythermal carp (Cyprinus carpio). J. exp. Biol, 80, 317–40.

    PubMed  CAS  Google Scholar 

  • Ikeda-Saito, M., Yonetani, T. and Gibson, Q.H. (1983) Oxygen equilibrium studies on hemoglobin from the bluefin tuna (Thunnus thynnus). J. mol. Biol, 168, 673–86.

    Article  PubMed  CAS  Google Scholar 

  • Itazawa, Y. and Takeda, T. (1978) Gas exchange in the carp gills in normoxic and hypoxic conditions. Respir. Physiol, 35, 263–9.

    Article  PubMed  CAS  Google Scholar 

  • Jensen, F.B. (1986) Pronounced influence of Hb-O2 saturation on red cell pH in tench blood in vivo and in vitro. J. exp. Zool, 238, 119–24.

    Article  PubMed  CAS  Google Scholar 

  • Jensen, F.B. (1987) Influences of exercise-stress and adrenaline upon intra-and extracellular acid-base status, electrolyte composition and respiratory properties of blood in tench (Tinca tinca) at different seasons. J. comp. Physiol, 157B, 51–60.

    Google Scholar 

  • Jensen, F.B. (1989) Hydrogen ion equilibria in fish haemoglobins. J. exp. Biol, 143, 225–34.

    PubMed  CAS  Google Scholar 

  • Jensen, F.B. (1990) Nitrite and red cell function in carp: control factors for nitrite entry, membrane potassium ion permeation, oxygen affinity and methaemoglobin formation. J. exp. Biol, 152, 149–66.

    Google Scholar 

  • Jensen, F.B. (1991) Multiple strategies in oxygen and carbon dioxide transport by haemoglobin, in Physiological Strategies for Gas Exchange and Metabolism (eds A.J. Woakes, M.K. Grieshaber and C.R. Bridges), Cambridge Univ. Press, Cambridge, pp. 55–78.

    Google Scholar 

  • Jensen, F.B. and Weber, R.E. (1982) Respiratory properties of tench blood and hemoglobin. Adaptation to hypoxic-hypercapnic water. Molec. Physiol, 2, 235–50.

    CAS  Google Scholar 

  • Jensen, F.B. and Weber, R.E. (1985) Kinetics of the acclimational responses of tench to combined hypoxia and hypercapnia. I and II. J. comp. Physiol, 156B, 197–211.

    Google Scholar 

  • Jensen, F.B. and Weber, R.E. (1987a) Internal hypoxia-hypercapnia in tench exposed to aluminium in acid water: effects on blood gas transport, acid-base status and electrolyte composition in arterial blood. J. exp. Biol, 127, 427–42.

    CAS  Google Scholar 

  • Jensen, F.B. and Weber, R.E. (1987b) Thermodynamic analysis of precisely measured oxygen equilibria of tench (Tinea tinea) hemoglobin and their dependence on ATP and protons. J. comp. Physiol, 157B, 137–43.

    Google Scholar 

  • Jensen, F.B., Andersen, N.A. and Heisler, N. (1987) Effects of nitrite exposure on blood respiratory properties, acid-base and electrolyte regulation in the carp (Cyprinus carpio). J. comp. Physiol, 157B, 533–41.

    Google Scholar 

  • Johnston, I.A. and Bernard, L.M. (1982) Routine oxygen consumption and characteristics of the myotomal muscle in tench: effects of long-term acclimation to hypoxia. Cell Tissue Res., 227, 161–77.

    PubMed  CAS  Google Scholar 

  • Jorgensen, B.B. (1980) Seasonal oxygen depletion in the bottom waters of a Danish fjord and its effects on the benthic community. Oikos, 34, 68–76.

    Article  Google Scholar 

  • Krogh, A. and Leitch, I. (1919) The respiratory function of the blood in fishes. J. Physiol, Lond., 52, 288–300.

    PubMed  CAS  Google Scholar 

  • Laursen, J.S., Andersen, N.A. and Lykkeboe, G. (1985) Temperature acclimation and oxygen binding properties of blood of the European eel, Anguilla anguilla. Comp. Biochem. Physiol, 81A, 79–86.

    Article  Google Scholar 

  • Lomholt, J.P. and Johansen, K. (1979) Hypoxia acclimation in carp-how it affects O2 uptake, ventilation, and O2 extraction from water. Physiol. Zool, 52, 38–49.

    Google Scholar 

  • McDonald, D.G. and Wood, CM. (1993) Branchial mechanisms of acclimation to metals in freshwater fish, in Fish Ecophysiology (eds J.C. Rankin and F.B. Jensen), Chapman and Hall, London, pp. 297–321.

    Google Scholar 

  • Malte, H. and Weber, R.E. (1987) The effect of shape and position of the oxygen equilibrium curve on extraction and ventilation requirement in fishes. Respir. Physiol, 70, 221–8.

    PubMed  CAS  Google Scholar 

  • Marinsky, C.A., Houston, A.H. and Murad, A. (1990) Effect of hypoxia on hemoglobin isomorph abundances in rainbow trout, Salmo gairdneri Can. J. Zool, 68, 884–8.

    Google Scholar 

  • Maxime, V., Peyraud-Waitzenegger, M., Claireaux, G. and Peyraud, C. (1990) Effects of rapid transfer from sea water to fresh water on respiratory variables, blood acid-base status and O2 affinity of haemoglobin in Atlantic salmon (Salmo salar L.). J. comp. Physiol, 160B, 31–9.

    Google Scholar 

  • Motais, R. and Garcia-Romeu, F. (1988) Effects of catecholamines and cyclic nucleotides on Na+/H+ exchange, in Na + /H + Exchange (ed. S. Grinstein), CRC Press, Boca Raton, FL, pp. 255–70.

    Google Scholar 

  • Motais, R., Garcia-Romeu, F. and Borgese, F. (1987) The control of Na+/H+ exchange by molecular oxygen in trout erythrocytes. A possible role of hemoglobin as a transducer. J, gen. Physiol, 90, 197–207.

    Article  CAS  Google Scholar 

  • Motais, R., Fievet, B., Garcia-Romeu, F. and Thomas, S. (1989) Na+-H+ exchange and pH regulation in red blood cells: role of uncatalyzed H2CO3 dehydration. Am. J. Physiol, 256, C728–35.

    PubMed  CAS  Google Scholar 

  • Muniz, LP. and Leivestad, H. (1980) Toxic effects of aluminium on the brown trout, Salmo trutta L., in Ecological Impact of Acid Precipitation (eds D. Draplos and A. Tollan). Johs. Grefslie Press, Mysen, Norway, pp. 320–21.

    Google Scholar 

  • Nikinmaa, M. (1982) Effects of adrenaline on red cell volume and concentration gradient of protons across the red cell membrane in the rainbow trout, Salmo gairdneri.Molec, Physiol, 2, 287–97

    CAS  Google Scholar 

  • Nikinmaa, M. (1983) Adrenergic regulation of haemoglobin oxygen affinity in rainbow trout red cells. J. comp. Physiol, 152, 67–72.

    CAS  Google Scholar 

  • Nikinmaa, M. (1990) Vertebrate Red Blood Cells. Adaptation of Function to Respiratory Requirements, Springer-Verlag, Berlin, 262 pp.

    Google Scholar 

  • Nikinmaa, M. and Jensen, F.B. (1986) Blood oxygen transport and acid-base status of stressed trout (Salmo gairdneri): pre-and postbranchial values in winter fish. Comp. Biochem. Physiol, 84A, 391–6.

    Article  Google Scholar 

  • Nikinmaa, M. and Jensen, F.B. (1992) Inhibition of adrenergic proton extrusion in rainbow trout red cells by nitrite-induced methaemoglobinaemia. J. Comp. Physiol. 162B, 429.

    Google Scholar 

  • Nikinmaa, M. and Tufts, B.L. (1989) Regulation of acid and ion transfer across the membrane of nucleated erythrocytes. Can. J. Zool, 67, 3039–45.

    Article  CAS  Google Scholar 

  • Nikinmaa, M., Cech, J.J., jun., Ryhunen, E.-L. and Salama, A. (1987) Red cell function of carp (Cyprinus carpio) in acute hypoxia. Exp. Biol, 47, 53–8.

    PubMed  CAS  Google Scholar 

  • Nikinmaa, M., Tuurala, H. and Soivio, A. (1980) Thermoacclimatory changes in blood oxygen binding properties and gill secondary lamellar structure of Salmo gairdneri. J. comp. Physiol, 140, 255–60.

    Google Scholar 

  • Nikinmaa, M., Soivio, A. and Railo, E. (1981) Blood volume of Salmo gairdneri: influence of ambient temperature. Comp. Biochem. Physiol, 69A, 767–9.

    Article  Google Scholar 

  • Nikinmaa, M., Tiihonen, K. and Paajaste, M. (1990) Adrenergic control of red cell pH in salmonid fish: roles of the sodium/proton exchange, Jacobs-Stewart cycle and membrane potential. J. exp. Biol, 154, 257–71.

    CAS  Google Scholar 

  • Nonnotte, G. and Truchot, J.-P. (1990) Time course of extracellular acid-base adjustments under hypo-and hyperosmotic conditions in the euryhaline fish Platichthys flesus. J. Fish Biol, 36, 181–90.

    Article  Google Scholar 

  • Perry, S.F. and Wood, C.M. (1989) Control and coordination of gas transfer in fishes. Can. J. Zool, 67, 2961–70.

    Article  Google Scholar 

  • Perry, S.F., Kinkead, R., Gallaugher, P. and Randall, D.J. (1989) Evidence that hypoxemia promotes catecholamine release during hypercapnic acidosis in rainbow trout (Salmo gairdneri). Respir. Physiol, 77, 351–64.

    Article  PubMed  CAS  Google Scholar 

  • Perutz, M.F. (1983) Species adaptation in a protein molecule. Mol Biol. Evol, 1, 1–28.

    PubMed  CAS  Google Scholar 

  • Randall, D. and Daxboeck, C. (1984) Oxygen and carbon dioxide transfer across fish gills, in Fish Physiology, Vol. XA (eds W.S. Hoar and D.J. Randall), Academic Press, New York, pp. 263–314.

    Google Scholar 

  • Salama, A. and Nikinmaa, M. (1988) The adrenergic responses of carp (Cyprinus carpio) red cells: effects of PO 2 and pH. J. exp. Biol, 136, 405–16.

    PubMed  CAS  Google Scholar 

  • Soivio, A. and Tuurala, H. (1981) Structural and circulatory responses to hypoxia in the secondary lamellae of Salmo gairdneri gills at two temperatures. J. comp. Physiol, 145, 37–43.

    Google Scholar 

  • Soivio, A., Nikinmaa, M. and Westman, K. (1980) The blood oxygen binding of hypoxic Salmo gairdneri. J. comp. Physiol, 136, 83–7.

    Google Scholar 

  • Speckner, W., Schindler, J.F. and Albers, C. (1989) Age-dependent changes in volume and haemoglobin content of erythrocytes in the carp (Cyprinus carpio). J. exp. Biol, 141, 133–49.

    PubMed  CAS  Google Scholar 

  • Stevens, E.D., Bennion, G.R., Randall, D.J. and Shelton, G. (1972) Factors affecting arterial pressures and blood flow from the heart in intact, unrestrained lingcod, Ophiodon elongatus. Comp. Biochem. Physiol, 45A, 681–95.

    Article  Google Scholar 

  • Tetens, V. and Christensen, N.J. (1987) Beta-adrenergic control of blood oxygen affinity in acutely hypoxia exposed rainbow trout. J. comp. Physiol, 157B, 667–75.

    Google Scholar 

  • Tetens, V. and Lykkeboe, G. (1985) Acute exposure of rainbow trout to mild and deep hypoxia: O2 affinity and O2 capacitance of arterial blood. Respir. Physiol, 61, 221–35.

    Article  PubMed  CAS  Google Scholar 

  • Tetens, V., Lykkeboe, G. and Christensen, N.J. (1988) Potency of adrenaline and noradrenaline for P-adrenergic proton extrusion from red cells of rainbow trout, Salmo gairdneri. J. exp. Biol, 134, 267–80.

    PubMed  CAS  Google Scholar 

  • Tetens, V., Wells, R.M.G. and DeVries, A.L. (1984) Antarctic fish blood: respiratory properties and the effects of thermal acclimation. J. exp. Biol, 109, 265–79.

    CAS  Google Scholar 

  • Thomas, S. (1983) Changes in blood acid-base balance in trout (Salmo gairdneri Richardson) following exposure to combined hypoxia and hypercapnia. J. comp. Physiol, 152, 53–7.

    CAS  Google Scholar 

  • Thomas, S. and Hughes, G.M. (1982) A study of the effects of hypoxia on acid-base status of rainbow trout blood using an extracorporeal blood circulation. Respir. Physiol, 49, 371–82.

    Article  PubMed  CAS  Google Scholar 

  • Thomas, S., Kinkead, R., Walsh, P.J., Wood, CM. and Perry, S.F. (1991) Desensitization of adrenaline-induced red blood cell H extrusion in vitro after chronic exposure of rainbow trout to moderate environmental hypoxia. J. exp. Biol, 156. 233–48.

    CAS  Google Scholar 

  • Van Assendelft, O.W. (1970) Spectrophotometry of Haemoglobin Derivatives, Royal Vangorcum, Assen, Netherlands, 152 pp.

    Google Scholar 

  • Weber, R.E. (1982) Intraspecific adaptation of hemoglobin function in fish to oxygen availability, in Exogenous and Endogenous Influences on Metabolic and Neural Controls (eds A.D.F. Addink and N. Spronk), Pergamon Press, Oxford, pp. 87–101.

    Google Scholar 

  • Weber, R.E. (1990) Functional significance and structural basis of multiple hemoglobins with special reference to ectothermic vertebrates, in Animal Nutrition and Transport Processes. 2. Transport, Respiration and Excretion: Comparative and Environmental Aspects (eds. J.-P. Truchot and B. Lahlou), Karger, Basel, pp. 58–75.

    Google Scholar 

  • Weber, R.E. and Jensen, F.B. (1988) Functional adaptations in hemoglobins from ectothermic vertebrates. A. Rev. Physiol, 50, 161–79.

    Article  CAS  Google Scholar 

  • Weber, R.E. and Lykkeboe, G. (1978) Respiratory adaptations in carp blood. Influences of hypoxia, red cell organic phosphates, divalent cations and CO? on hemoglobin oxygen affinity. J. comp. Physiol, 128, 127–37.

    Article  CAS  Google Scholar 

  • Weber, R.E., Jensen, F.B. and Cox, R.P. (1987) Analysis of teleost hemoglobin by Adair and Monod-Wyman-Changeux models. Effects of nucleoside triphosphates and pH on oxygenation of tench hemoglobin. J. comp. Physiol 157B, 145–52.

    Google Scholar 

  • Weber, R.E., Wood, S.C and Lomholt, J.P. (1976) Temperature acclimation and oxygen binding properties of blood and multiple haemoglobins of rainbow trout. J exp. Biol.. 65, 333–45.

    PubMed  CAS  Google Scholar 

  • Wells, R.M.G., Grigg, G.C, Beard, L.A. and Summers, G. (1989) Hypoxic responses in a fish from a stable environment: blood oxygen transport in the Antarctic fish Pagothenia borchgrevinki. J. exp. Biol, 141, 97–111.

    Google Scholar 

  • Wood, C.M. (1989) The physiological problems offish in acid waters, in Acid Toxicity and Aquatic Animals (eds R. Morris, E.W. Taylor, D.J.A. Brown and J.A Brown). Cambridge Univ. Press, Cambridge, pp. 125–52.

    Google Scholar 

  • Wood, S.C. (1991) Interactions between hypoxia and hypothermia. A. Rev. Physiol. 53, 71–85.

    Article  CAS  Google Scholar 

  • Wood, S.C and Johansen, K. (1972) Adaptation to hypoxia by increased HbO2 affinity and decreased red cell ATP concentration. Nature New Biol, 237, 278–9.

    PubMed  CAS  Google Scholar 

  • Wood, S.C and Johansen, K. (1973) Organic phosphate metabolism in nucleated red cells: influence of hypoxia on eel HbO2 affinity. Neth. J. Sea Res., 7, 328–38.

    Article  CAS  Google Scholar 

  • Wyman, J. (1948) Heme proteins. Adv. Protein Chem., 4, 407–531.

    Article  PubMed  CAS  Google Scholar 

  • Yamamoto, K., Itazawa, Y. and Kobayashi, H. (1985) Direct observation offish spleen by an abdominal window and its application to exercised and hypoxic vellowtail. Jap. J. Ichthyol, 31, 427–33.

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1993 Chapman & Hall

About this chapter

Cite this chapter

Jensen, F.B., Nikinmaa, M., Weber, R.E. (1993). Environmental perturbations of oxygen transport in teleost fishes: causes, consequences and compensations. In: Rankin, J.C., Jensen, F.B. (eds) Fish Ecophysiology. Chapman & Hall Fish and Fisheries Series, vol 9. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-2304-4_6

Download citation

  • DOI: https://doi.org/10.1007/978-94-011-2304-4_6

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-0-412-45920-7

  • Online ISBN: 978-94-011-2304-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics