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Other soft tissue tumours

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Paediatric Neoplasia

Part of the book series: Current Histopathology ((CUHI,volume 22))

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Abstract

Soft tissue tumours in childhood are histogenetically diverse, comprising a wide range of entities that vary considerably in prevalence, anatomical location and metastatic potential. They have been already discussed to some extent in the preceding chapters, e.g. fibromatosis and rhabdomyosarcoma. This chapter deals essentially with remaining soft tissue entities that are likely to occur in children. Some are seen specifically as childhood tumours while others, occurring more commonly in the older population, are seen from time to time in children, and are therefore also considered here.

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References

  1. Enzinger F.M., Weiss S.W. Neurofibromatosis von Recklinghausen’s disease). In: Enzinger F.M., Weiss S.W., editors. Soft tissue tumors. St Louis, Toronto, London: C.V. Mosby; 1983:606–15

    Google Scholar 

  2. Raffensperger J, Cohen R. Plexiform neurofibromas in childhood. J Pediatr Surg. 1972;7:144–51.

    Article  PubMed  CAS  Google Scholar 

  3. Coffin C.M., Dehner L.P. Cellular peripheral neural tumors (neurofibromas) in children and adolescents: a clinicopathological and immunohistochemical study. Pediatr Pathol. 1990;10:351–61.

    Article  PubMed  CAS  Google Scholar 

  4. Gallager R.L., Helwig E.B. Neurothekeoma-a benign cutaneous tumor of neural origin. Am J Clin Pathol. 1980;74:759–64

    PubMed  CAS  Google Scholar 

  5. Abell M.A. Hart W.R., Olson J.R. Tumors of the peripheral nervous system. Hum Pathol. 1970;1:503–51.

    PubMed  CAS  Google Scholar 

  6. Fletcher C.D.M. Peripheral nerve sheath tumors. Pathol Annu. 1990;2:53–74.

    Google Scholar 

  7. Meis J.M., Enzinger F.M., Martz K.L., Neal J.A. Malignant peripheral nerve sheath tumors (malignant schwannomas) in children. Am J Surg Pathol. 1992;16:694–707.

    Article  PubMed  CAS  Google Scholar 

  8. Lack E.E., Worsham G.F., Callihan M.D., Crawford B.E., Vawter G.F. Gingival granular cell tumors of the newborn (congenital ‘epulis’): a clinical and pathologic study of 21 patients. Am J Surg Pathol. 1981;5:37–46.

    Article  PubMed  CAS  Google Scholar 

  9. Lifshitz M.S., Flotte T.J., Greco M.A. Congenital granular cell epulis. Immunohistochemical and ultrastructural observations. Cancer. 1984;53:1845–8.

    Article  PubMed  CAS  Google Scholar 

  10. Tucker M.C., Rusnock E.J. Azumi N, Hoy G.R., Lack E.E. Gingival granular cell tumors of the newborn. An ultrastructural and immunohistochemical study. Arch Pathol Lab Med. 1990;114:895–8.

    PubMed  CAS  Google Scholar 

  11. Park S.H., Kim T.J., Chi Je G. Congenital granular cell tumor with systemic involvement. Immunohistochemical and ultrastructural study. Arch Pathol Lab Med. 1991;115;934–8.

    PubMed  CAS  Google Scholar 

  12. Chung E.B. Pitfalls in diagnosing benign soft tissue tumors in infancy and childhood. Pathol Annu. 1985;20:323–86.

    PubMed  Google Scholar 

  13. Regezi J.A. Zarbo R.J., Courtney R.M., Crissman J.D. Imunoreactivity of granular cell lesions of skin, mucosa, and jaw. Cancer. 1989;64;1455–60.

    Article  PubMed  CAS  Google Scholar 

  14. Chung E.B., Enzinger F.M. Benign lipoblastomatosis. An analysis of 35 cases. Cancer. 1973;32:482–92.

    Article  PubMed  CAS  Google Scholar 

  15. Chaudhuri B, Ronan S.G., Ghosh L. Benign lipoblastoma. A case report. Cancer. 1980;46:611–14.

    Article  PubMed  CAS  Google Scholar 

  16. Abdul-Karim F.W., Evans H.L., Silva E.G. Giant cell fibroblastoma: a report of three cases. Am J Clin Pathol. 1985;83:165–70.

    PubMed  CAS  Google Scholar 

  17. Dymock R.B., Allen P.W., Sterling J.W., Gilbert E.F., Thornbery J.M. Giant cell fibroblastoma. A distinctive, recurrent tumor of childhood. Am J Surg Pathol. 1987;11:263–71.

    Article  PubMed  CAS  Google Scholar 

  18. Chou P, Gonzalez-Crussi F. Mangkornkanok M. Giant cell fibroblastoma. Cancer. 1989;63:756–62.

    Article  PubMed  CAS  Google Scholar 

  19. Fletcher C.O.M. Giant cell fibroblastoma of soft tissue: a clinicopathological and immunohistochemical study. Histopathology. 1988;13:499–508.

    Article  PubMed  CAS  Google Scholar 

  20. Shmookler B.M., Enzinger F.M., Weiss W.W. Giant cell fibroblastoma. A juvenile form of dermatofibrosarcoma protruberans. Cancer. 1989;64:2154–61.

    Article  PubMed  CAS  Google Scholar 

  21. Beham A. Fletcher C.D.M. Dermatofibrosarcoma protruberans with areas resembling giant cell fibroblastoma: a report of two cases. Histopathology. 1990;17:165–7.

    Article  PubMed  CAS  Google Scholar 

  22. Alguacil-Garcia A. Giant cell fibroblastoma recurring as dermatofibrosarcoma protruberans. Am J Surg Pathol. 1991;15:798–801.

    Article  PubMed  CAS  Google Scholar 

  23. McKee P.H., Fletcher C.D.M. Dermatofibrosarcoma protruberans presenting in infancy and childhood. J Cutan Pathol. 1991;18:241–6.

    Article  PubMed  CAS  Google Scholar 

  24. Enzinger F.M., Zhang R. Plexiform fibrohistiocytic tumor in children and young adults. An analysis of 65 cases. Am J Surg Pathol. 1988;12;818–26.

    Article  PubMed  CAS  Google Scholar 

  25. Hollowood K, Holley M.P., Fletcher C.D.M. Plexiform fibrohistiocytic tumour: clinicopathological. immunohistochemical and ultrastructural analysis in favour of a myofibroblastic lesion. Histopathology. 1991;19:503–13.

    Article  PubMed  CAS  Google Scholar 

  26. Enzinger F.M. Angiomatoid malignant fibrous histiocytoma. A distinctive fibrohistiocytic tumor of children and young adults simulating a vascular neoplasm. Cancer. 1979;44:2147–57.

    Article  PubMed  CAS  Google Scholar 

  27. Costa M.J., Weiss S.W. Angiomatoid malignant fibrous histiocytoma. A follow-up study of 108 cases with evaluation of possible histological predictors of outcome. Am J Surg Pathol. 1990;14:1126–32.

    Article  PubMed  CAS  Google Scholar 

  28. Fletcher C.D.M. Angiomatoid ‘malignant fibrous histiocytoma’. An immunohistochemical study indicative of myoid differentiation. Hum Pathol. 1991;22:563–8.

    Article  PubMed  CAS  Google Scholar 

  29. Argenyi Z.B., Van Rybroek J.J., Kemp J.D., Soper R.T. Congenital angiomatoid malignant fibrous histiocytoma. A light-microscopic, immunopathologic, and electron-microscopic study. Am J Dermatopathol. 1988;10:59–67.

    Article  PubMed  CAS  Google Scholar 

  30. Enzinger F.M., Shiraki M. Extraskeletal myxoid chondrosarcoma. An analysis of 34 cases. Hum Pathol. 1972;3:421–35.

    Article  PubMed  CAS  Google Scholar 

  31. Hachitanda Y, Tsuneyoshi M, Daimaru Y et al. Extraskeletal myxoid chondrosarcoma in young children. Cancer. 1988;61:2521–6.

    Article  PubMed  CAS  Google Scholar 

  32. Jessurun J, Rojas M.E., Albores-Saavedra J. Congenital extraskeletal chondrosarcoma. J Bone Jt Surg. 1982;64:293–6.

    CAS  Google Scholar 

  33. Coffin C.M., Dehner L.P. Soft tissue neoplasms in childhood: a clinicopatholic overview. In: Finegold M, editor. Pathology of neoplasia in children and adolescents. Philadelphia: W.B. Saunders; 1986:223–55.

    Google Scholar 

  34. Bernstein K.E., Lattes R. Nodular (pseudosarcomatous) fasciitis, a nonrecurreni lesion: clinicopathological study of 134 cases. Cancer. 1982;49;1668–78.

    Article  PubMed  CAS  Google Scholar 

  35. Montgomery E.A. Meis J.M. Nodular fasciitis. Its morphological spectrum and immunohistochemical profile. Am J Surg Pathol. 1991;15:942–8.

    Article  PubMed  CAS  Google Scholar 

  36. Lauer D.H., Enzinger F.M. Cranial fasciitis of childhood. Cancer. 1980;45:401–6.

    Article  PubMed  CAS  Google Scholar 

  37. Suster S, Rosai J. Hamartoma of the scalp with ectopic meningothelial elements. A distinctive benign soft tissue lesion that may simulate angiosarcoma. Am J Surg Pathol. 1990;14:1–11.

    Article  PubMed  CAS  Google Scholar 

  38. Bale P.M., Hughes L, de Silva M. Sequestrated meningoceles of scalp: extracranial meningeal heterotopia. Hum Pathol. 1990;21:1156–63.

    Article  PubMed  CAS  Google Scholar 

  39. Enzinger F.M., Weiss S.W. Alveolar soft part sarcoma. In: Enzinger F.M., Weiss S.W., editors. Soft tissue tumors. St. Louis, Toronto, London: C.V. Mosby; 1983:780–87.

    Google Scholar 

  40. Schmidt D, Thum P, Harms D, Treuner J. Synovial sarcoma in children and adolescents. A report from the Kiel Pediatric Tumor Registry. Cancer. 1991;67:1667–72.

    Article  PubMed  CAS  Google Scholar 

  41. Enzinger F.M., Weiss S.W. Synovial sarcoma. In: Enzinger F.M., Weiss S.W., editors. Soft tissue tumors. St Louis, Toronto, London C.V. Mosby; 1983:519–49.

    Google Scholar 

  42. Smith S, Reeves B.R., Wong L, Fisher C. A consistent chromosome translocation in synovial sarcoma. Cancer Genet Cytogenet. 1987;26;179–80.

    Article  PubMed  CAS  Google Scholar 

  43. Enzinger F.M., Weiss S.W. Myositis ossificans. In: Enziger F.M., Weiss S.W., editors. Soft tissue tumors. St Louis, Toronto, London: C.V. Mosby; 1983:720–9.

    Google Scholar 

  44. Cramer S.F., Ruehl A. Mandel M.A. Fibrodysplasia ossificans progressiva. A distinctive bone-forming lesion of the soft tissue. Cancer. 1981;48;1016–21.

    Article  PubMed  CAS  Google Scholar 

  45. Myers B.W., Masi A.T., Feigenbaum S.L. Pigmented villonodular synovitis and tenosynovitis: a clinical epidemiologic study of 166 cases and review of the literature. Medicine. 1980;59:223–38.

    Article  PubMed  CAS  Google Scholar 

  46. Wood G.S., Beckstead J.H., Medeiros L.J., Kempson R.L., Warnke R.A. The cells of giant cell tumour of tendon sheath resemble osteoclasts. Am J Surg Pathol. 1988;12:444–52.

    Article  PubMed  CAS  Google Scholar 

  47. Enzinger F.M., Weiss S.W. Fibroma of tendon sheath. In: Enzinger F.M., Weiss S.W., editors. Soft tissue tumors. St Louis, Toronto, London: C.V. Mosby; 1983:31–3.

    Google Scholar 

  48. Chung E.B., Enzinger F.M. Fibroma of tendon sheath. Cancer. 1979;44;1945–54.

    Article  PubMed  CAS  Google Scholar 

  49. Pulitzer D.R., Martin P.C., Reed R.J. Fibroma of tendon sheath. A clinicopathologic study of 32 cases. Am J Surg Pathol. 1989;13:472–9.

    Article  PubMed  CAS  Google Scholar 

  50. Heffner R.R., Armbrustmacher V.W., Earle K.M. Focal myositis. Cancer. 1977;40:301–6.

    Article  PubMed  Google Scholar 

  51. Markel S.F., Enzinger F.M. Neuromuscular hamartoma-a benign ‘Triton tumor’ composed of mature neural and striated muscle elements. Cancer. 1982;49:140–4.

    Article  PubMed  CAS  Google Scholar 

  52. Gonzalez-Crussi F, Goldschmidt R.A. Hsueh W et al. Infantile sarcoma with intracytoplasmic filamentous inclusions. Cancer. 1982;49:2365–75.

    Article  PubMed  CAS  Google Scholar 

  53. Tsuneyoshi M, Daimaru Y, Hashimoto H, Enjoji M. Malignant soft tissue neoplasms with the histologic features of renal rhabdoid tumors: an ultrastructural and immunohistochemical study. Hum Pathol. 1985;16;1235–42.

    Article  PubMed  CAS  Google Scholar 

  54. Perrone T, Swanson P.E., Twiggs L, Ulbright T.M., Dehner L.P. Malignant rhabdoid tumour of the vulva: is distinction from epithelioid sarcoma possible? A pathologic and immunohistochemical study. Am J Surg Pathol. 1989;13:848–58.

    Article  PubMed  CAS  Google Scholar 

  55. Kodet R, Newton W.A. Sachs N et al. Rhabdoid tumors of softtissues: a clinicopathologic study of 26 cases enrolled onthe Intergroup Rhabdo-myosarcoma Study. Hum Pathol. 1991;22:674–84.

    Article  PubMed  CAS  Google Scholar 

  56. Berry P.J. Vujanic G.M. Commentary: Malignant rhabdoid tumour. Histopathology. 1992;20:189–93.

    Article  PubMed  CAS  Google Scholar 

  57. Chase D.R. Enzinger F.M. Epithelioid sarcoma. Diagnosis, prognostic indicators. and treatment. Am J Surg Pathol. 1985;9:241–63.

    Article  PubMed  CAS  Google Scholar 

  58. Enzinger F.M. Epithelioid sarcoma. A sarcoma simulating a granuloma or a carcinoma. Cancer. 1970;26:1029–41.

    Article  PubMed  CAS  Google Scholar 

  59. Schmidt D. Harms D. Epithelioid sarcoma in children and adolescents. An immunohistochemical study. Virchows Arch. A. 1987;410:423–31.

    Article  CAS  Google Scholar 

  60. Fisher C. Epithelioid sarcoma: the spectrum of ultrastructural differentiation in seven immunohistochemically defined cases. Hum Pathol. 1988;19:255–75.

    Article  Google Scholar 

  61. Pettinato G. Manivel J.C. De Rosa N. Dehner L.P. Inflammatory myofibroblastic tumor (plasma cell granuloma). Clinicopathologic study of 20 cases with immunohistochemical and ultrastructural observations. Am J Clin Pathol. 1990;94:538–46.

    PubMed  CAS  Google Scholar 

  62. Scott L. Blair G. Taylor G. Dimmick J. Fraser G. Inflammatory pseudotumors in children. J Pediatr Surg. 1988;23:755–8.

    Article  PubMed  CAS  Google Scholar 

  63. Berardi R.S. Lee S.S. Chen H.P. Stines G.J. Inflammatory pseudotumor of the lung. Surg Gynecol Obstet. 1983;156:89–96.

    PubMed  CAS  Google Scholar 

  64. Chen K.T. Inflammatory pseudotumour of the liver. Hum Pathol. 1984;15:694–6.

    Article  PubMed  CAS  Google Scholar 

  65. Meis J.M. Enzinger F.M. Inflammatory fibrosarcoma of the mesentery and retroperitoneum. A tumor closely simulating inflammatory pseudotumor. Am J Surg Pathol. 1991;15:1146–56.

    Article  PubMed  CAS  Google Scholar 

  66. Le Ber M.S. Stout A.P. Benign mesenchymomas in children. Cancer. 1962;15:598–605.

    Article  PubMed  CAS  Google Scholar 

  67. Bures C. Barnes L. Benign mesenchymomas of the head and neck. Arch Pathol Lab Med. 1978;102:237–41.

    PubMed  CAS  Google Scholar 

  68. Newman P.L. Fletcher C.D.M. Malignant mesenchymoma. Clinicopathologic analysis of a series with evidence of low-grade behavior. Am J Surg Pathol. 1991;15:607–14.

    Article  PubMed  CAS  Google Scholar 

  69. Enzinger F.M. Weiss S.W. Malignant mesenchymoma. In: Enzinger F.M. Weiss S.W. editors. Soft tissue tumours. St Louis. Toronto. London: C.V. Mosby; 1983:808–10.

    Google Scholar 

  70. Shmookler B.M. Enzinger F.M. Liposarcoma occurring in children. An analysis of 17 cases and review of the literature. Cancer. 1983;52:567–74.

    Article  PubMed  CAS  Google Scholar 

  71. Weiss S.W. Enzinger F.M. Malignant fibrous histiocytoma. An analysis of 200 cases. Cancer. 1978:41:2250–66.

    Article  PubMed  CAS  Google Scholar 

  72. Zuppan C.W. Mierau G.W. Wilson H.L. Malignant fibrous histiocytoma in childhood: a report of two cases and review of the literature. Pediatr Pathol. 1987;7:303–18.

    Article  PubMed  CAS  Google Scholar 

  73. Nemes Z. Thomazy V. Factor Xilia and the classic histiocytic markers in malignant fibrous histiocytoma: a comparative immunohistochemical study. Hum Pathol. 1988;19:822–9.

    Article  PubMed  CAS  Google Scholar 

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© 1993 S. Variend

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Variend, S. (1993). Other soft tissue tumours. In: Paediatric Neoplasia. Current Histopathology, vol 22. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-2224-5_14

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  • DOI: https://doi.org/10.1007/978-94-011-2224-5_14

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