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Molecular genetics of C1-inhibitor and hereditary angiooedema

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Complement in Health and Disease

Part of the book series: Immunology and Medicine ((IMME,volume 20))

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Abstract

The hereditary transmission of angioneurotic oedema was documented as early as 1888 by the remarkable pedigree investigations of W. Osier1. His work and subsequent family studies led to the recognition of the autosomal dominant mode of transmission of the disease2.

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  1. M. Tosi
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Editors and Affiliations

  1. Department of Immunology, University of Leicester, Leicester, UK

    K. Whaley

  2. Institut für Medizinische Mikrobiologie, University of Mainz, Mainz, Germany

    M. Loos

  3. University of Iowa, Iowa City, Iowa, USA

    J. M. Weiler

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Tosi, M. (1993). Molecular genetics of C1-inhibitor and hereditary angiooedema. In: Whaley, K., Loos, M., Weiler, J.M. (eds) Complement in Health and Disease. Immunology and Medicine, vol 20. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-2214-6_9

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