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Metabolic and Storage Disorders

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Atlas of Liver Pathology

Part of the book series: Current Histopathology ((CUHI,volume 23))

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Abstract

Many of the inherited metabolic disorders affect the liver. However, outside specialist centres, most pathologists will see only a handful of cases in a working lifetime and thus only the commonest and best defined morphologically will be discussed in any detail in this section. More detailed accounts of these and rarer disorders are available elsewhere1–4.

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References

  1. Ishak, K. G. and Sharp, H. L. (1987). Metabolic errors and liver disease. In MacSween, R. N. M., Anthony, P. P. and Scheuer, P. J. (eds). Pathology of the liver. 2nd edn. pp. 99–180. Edinburgh: Churchill Livingstone

    Google Scholar 

  2. Filipe, M. I. and Lake, B. D. (1990). Histochemistry in Pathology. Edinburgh: Churchill Livingstone

    Google Scholar 

  3. Stanbury, B., Wyngarden, J. B., Fredrickson, D. S., Goldstein, J. L. and Brown, M. S. (eds.). (1983). The Metabolic Basis of Inherited Disease. 5th edn. New York: McGraw-Hill.

    Google Scholar 

  4. Ghishan, F. K. and Greene, H. L. (1990). Inborn errors of metabolism that lead to permanent liver injury. In Zakim, D. and Boyer, T. D. (eds). Hepatology. A textbook of liver disease. 2nd edn. pp. 1300–1348. Philadelphia: Saunders

    Google Scholar 

  5. James, S. P., Stomeyer, F. W. and Chang, C. (1981). Liver abnormalities in patients with Gaucher’s disease. Gastroeneterology, 80, 126–133

    CAS  Google Scholar 

  6. Wenger, D. A., Barth, G. and Githens, J. H. (1977). Nine cases of sphingomyelin lipidosis, a new variant in Spanish American children. Juvenile variant of Niemann-Pick disease with foamy and sea-blue histiocytes. Am. J. Dis. Child., 131, 955–961

    PubMed  CAS  Google Scholar 

  7. Portmann, B. C. (1993). Paediatric liver disease. In Wight, D. G. D. (eds). Liver, Biliary Tract and Exocrine Pancreas. 3rd edn. Vol. 11. Systemic Pathology. Symmers, W. S. C. Series ed. Edinburgh: Churchill Livingstone

    Google Scholar 

  8. Beaudet, A. L., Ferry, G. D., Nichols, B. L. and Rosenberg, H. S. (1977). Cholesterol ester storage disease: clinical, biochemical and pathological studies. J. Pediatr., 90, 910–914

    Article  PubMed  CAS  Google Scholar 

  9. Bale, P. M., Clifton-Bligh, P., Benjamin, B. N. P. and Whyte, H. M. (1971). Pathology of Tangier disease. J. Clin. Pathol., 24, 609–616

    Article  PubMed  CAS  Google Scholar 

  10. Kelly, T. E. (1976). The mucopolysaccharidoses and mucolipidoses. Clin. Orthop., 114, 116–136

    PubMed  Google Scholar 

  11. Spranger, J. (1975). Mucolipidoses 1. In Bergsma, D. (eds). Disorders of Connective Tissue. New York: Stratton Intercontinental Medical Book Corporation

    Google Scholar 

  12. McAdams, A. J., Hug, G. and Bove, K. E. (1974). Glycogen storage disease, types I to X. Criteria for morphological diagnosis. Hum. Pathol., 5, 463–487

    Article  PubMed  CAS  Google Scholar 

  13. Fink, A. S., Appleman, H. D. and Thompson, N. W. (1985). Hemorrhage into a hepatic adenoma and type la glycogen storage disease: a case report and review of the literature. Surgery, 97, 117–124

    PubMed  CAS  Google Scholar 

  14. Segal, S. (1983). Disorders of galactose metabolism. In Stanbury, B., Wyngarden, J. B., Fredrickson, D. S., Goldstein, J. L. and Brown, M. S. (eds). The Metabolic Basis of Inherited Disease. 5th edn. pp. 161–191. New York: McGraw-Hill

    Google Scholar 

  15. Monk, A. M., Mitchell, A. J. H. and Milligan, D. W. A. (1977). The diagnosis of classical galactosaemia. Arch. Dis. Child., 52, 943–946

    Article  PubMed  CAS  Google Scholar 

  16. Gitzelman, R., Steinmann, B. and van den Berghe, G. (1983). Essential fructosuria, hereditary fructose intolerance, and fructose 1,6-diphosphatase deficiency. In Stanbury, B., Wyngarden, J. B., Fredrickson, D. S., Goldstein, J. L. and Brown, M. S. (eds). The Metabolic Basis of Inherited Disease. 5th edn. pp. 118–140. New York: McGraw-Hill

    Google Scholar 

  17. Schulte, M. J. and Lenz, W. (1977). Fatal sorbitol infusion in a patient with fructose-sorbitol intolerance [letter]. Lancet, 2, 188

    Article  PubMed  CAS  Google Scholar 

  18. Prive, L. (1967). Pathological findings in patients with tyrosinaemia. Can. Med. Assoc. J., 97, 1054–1056

    PubMed  CAS  Google Scholar 

  19. Dehner, L. P., Snover, D. C., Sharp, H. L., Asher, N. A., Nakhleh, R. and Day, D. L. (1989). Hereditary tyrosinaemia type I (chronic form): Pathologic findings in the liver. Hum. Pathol., 20, 149–158

    Article  PubMed  CAS  Google Scholar 

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© 1993 D. G. D. Wight

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Wight, D.G.D. (1993). Metabolic and Storage Disorders. In: Atlas of Liver Pathology. Current Histopathology, vol 23. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-2212-2_9

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  • DOI: https://doi.org/10.1007/978-94-011-2212-2_9

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-4980-1

  • Online ISBN: 978-94-011-2212-2

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