Skip to main content
SpringerLink
Log in

Benign Tumours and Tumour-like Conditions

  • Chapter
Atlas of Liver Pathology

Part of the book series: Current Histopathology ((CUHI,volume 23))

  • 248 Accesses

Abstract

Tumour-like conditions may arise from any of the component cells of the liver, including hepatocytes, bile ducts and endothelium. They are classified in Table 22.1.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Butron Vila, M. M., Haot, J. and Desmet, V. J. (1980). Cholestatic features in nodular hyperplasia of the liver. Hum. Pathol, 11, 181–186

    Article  Google Scholar 

  2. Knowles, D. M., Casarella, W. J., Johnson, P. M. and Wolff, M. (1978). The clinical radiologic, and pathologic characterization of benign hepatic neoplasms. Alleged association with oral contraceptives. Medicine (Baltimore). 57,223–237

    Google Scholar 

  3. Stocker, J. T. and Ishak, K. G. (1981). Focal nodular hyperplasia of the liver: a study of 21 pediatric cases. Cancer, 48, 336–345

    Article  PubMed  CAS  Google Scholar 

  4. Ishak, K. G. (1988). Benign tumors and pseudotumors of the liver. Appl. Pathol., 6, 82–104

    CAS  Google Scholar 

  5. Moesner, J. (1977). Focal nodular hyperplasia of the liver. Possible influence of female reproductive steroids on the histological picture. Acta Path Microbiol Scand [A], 85,113–121

    Google Scholar 

  6. Lough, J., Spicer, P. and Kinch, R. (1980). Focal nodular hyperplasia of the liver. EM study of vascular lesions. Hum Pathol, 11, 181–186

    Article  PubMed  CAS  Google Scholar 

  7. Wanless, I. R., Mawdsley, C. and Adams, R. (1985). On the pathogenesis of focal nodular hyperplasia of the liver. Hepatology, 5,1194–1200

    Article  PubMed  CAS  Google Scholar 

  8. Mathieu, D., Zafrani, E. S., Anglade, M. C. and Dhumeaux, D. (1989). Association of focal nodular hyperplasia and hepatic hemangioma. Gastroenterology, 97, 154–157

    PubMed  CAS  Google Scholar 

  9. Goldin, R. D. and Rose, D. S. (1990). Focal nodular hyperplasia of the liver associated with intracranial vascular malformations. Gut, 31,554–555

    Article  PubMed  CAS  Google Scholar 

  10. Vecchio, F. M. (1988). Fibrolamellar carcinoma of the liver: a distinct entity within the hepatocellular tumors. A review. Appl Pathol, 6, 139–148

    PubMed  CAS  Google Scholar 

  11. Paradinas, F. J. (1993). Liver tumours and tumour-like conditions. In Wight, D. G. D. (ed). Liver, Biliary Tract and Exocrine Pancreas. Vol. 11. Systemic Pathology. Symmers, W. S. C. Series ed. 3rd edn. Edinburgh: Churchill Livingstone

    Google Scholar 

  12. Brophy, C. M., Bock, J. F., West, A. B. and McKhann, C. F. (1989). Liver cell adenoma: diagnosis and treatment of a rare hepatic neoplastic process. Am J Gastroenterol, 84, 429–432

    PubMed  CAS  Google Scholar 

  13. Phillips, M. J., Langer, B., Stone, R., Fisher, M. M. and Ritchie, S. (1973). Benign liver tumours, classification and ultrastructural pathology. Cancer, 32, 463–470

    Article  PubMed  CAS  Google Scholar 

  14. Gold, J. H., Guzman, 1. J. and Rosai, J. (1978). Benign tumours of the liver. Pathological examination of 45 cases. Am J Clin Pathol, 70, 6–17

    CAS  Google Scholar 

  15. Craig, J. R. Peters, R. L. and Edmondson, H. A. (1989). Tumors of the liver and intrahepatic bile ducts. In Atlas of Tumour Pathology. Fascicle 26. Second series. Washington DC: AFIP

    Google Scholar 

  16. Baum, J. I., Holtz, F., Bookstein, J. J. and Klein, E. W. (1973). Possible association between benign hepatomas and oral contraceptives. Lancet, 1,926–929

    Article  Google Scholar 

  17. Fechner, R. E. (1977). Benign hepatic lesions and orally administered contraceptives. Report of seven cases and analysis of the literature. Hum Pathol, 8, 255–268

    Article  PubMed  CAS  Google Scholar 

  18. Klatskin, G. (1977). Hepatic tumours: possible relationship to use of oral contraceptives. Gastroenterology, 73, 386–394

    PubMed  CAS  Google Scholar 

  19. Nime, F., Pickren, J. W., Vana, J., Aronoff, B. L., Baker, H. W. and P, M. G. (1979). Histology of liver tumours in oral contraceptive users observed during a national survey by American College of Surgeons Commission on Cancer. Cancer, 44,1481–1489

    Article  PubMed  CAS  Google Scholar 

  20. Edmondson, H. A., Henderson, B. and Benton, B. (1975). Liver cell adenomas associated with use of oral contraceptives. N Engl J Med, 294, 470–472

    Article  Google Scholar 

  21. Winkler, K. and Poulson, H. (1975). Liver disease with periportal sinusoidal dilatation. A possible complication to contraceptive steroids. Scand J Gastroenterol, 10. 699–704

    PubMed  CAS  Google Scholar 

  22. Mays, E. T., Christofferson, W. M. and Williams, H. C. (1976). Hepatic changes in young women ingesting contraceptive steroids: hepatic haemorrhage and primary hepatic tumours. J Am Med Assoc, 235, 730–732

    Article  CAS  Google Scholar 

  23. Glassberg, A. B. and Rosenbaum, E. H. (1976). Oral contraceptives and malignant hepatoma. Lancet, 1, 479

    Article  PubMed  CAS  Google Scholar 

  24. Tigano, F., Terlazzo, B. and Barrile, A. (1976). Oral contraceptives and malignant hepatoma. Lancet, 2, 196

    Article  PubMed  CAS  Google Scholar 

  25. Davis, M., Portmann, B., Searle, M., Wright, R. and Williams, R. (1975). Histological evidence of carcinoma in a hepatic tumour associated with oral contraceptives. Br. Med J. 4, 496–498

    Article  PubMed  CAS  Google Scholar 

  26. Galloway, S. J., Casarella, W. J., Lattes, R. and Seaman, W. B. (1975). Minimal deviation hepatoma: a new entity. Am J Roentgenol. Radium Ther Nucl Med, 125, 184–192

    Article  PubMed  CAS  Google Scholar 

  27. Goldfarb, S. (1976). Sex hormones and hepatic neoplasia. Cancer Res, 36, 2584–2588

    PubMed  CAS  Google Scholar 

  28. Vessey, M. P., Kay, C. R., Baldwin, J. A., Clarke, J. A. and Macleod, J. B. (1977). Oral contraceptives and benign liver tumours. Br. Med. J., 1. 1064–1065

    Article  PubMed  CAS  Google Scholar 

  29. Heston, W. E., Vlahakis, G. and Desmukes, B. (1973). Effects of the antifertility drug Enovid in five strains of mice, with particular regard to carcinogenesis. J Natl Cancer Inst, 51, 209–224

    PubMed  CAS  Google Scholar 

  30. Anthony, P. P. (1988). Liver tumours. Baillières Clin Gastroenterol, 2, 501–522

    Article  PubMed  CAS  Google Scholar 

  31. Paradinas, F. J., Bull, T. B., Westaby, D. and Murray-Lyon, I. M. (1977). Hyperplasia and prolapse of hepatocytes into hepatic veins during long-term methyl testosterone therapy: possible relationships of these changes to the development of peliosis hepatis and liver tumours. Histopathology, 1, 225–246

    Article  PubMed  CAS  Google Scholar 

  32. Anthony, P. P. (1975). Hepatoma associated with androgenic steroids. Lancet, 1,685–686

    Article  PubMed  CAS  Google Scholar 

  33. See, K. L., See, M. and Gluud, C. (1992). Liver pathology associated with the use of anabolic-androgenic steroids. Liver, 12,73–79

    Article  Google Scholar 

  34. Sweeney, E. C. and Evans, D. J. (1976). Hepatic lesions in patients treated with synthetic anabolic steroids. J. Clin. Pathol., 29. 626–633

    Article  PubMed  CAS  Google Scholar 

  35. Steiner, P. E. (1959). Nodular regenerative hyperplasia of the liver. Am. J. Pathol., 35, 943–947

    PubMed  CAS  Google Scholar 

  36. Wanless, J. R., Goodwin, T. A., Allen, F. and Feder, A. (1980). Nodular regenerative hyperplasia of the liver in haematologic disorders: a possible response to obliterative portal venopathy. A morpho-metric study of nine cases with an hypothesis on the pathogenesis. Medicine (Baltimore), 59, 367–369

    CAS  Google Scholar 

  37. Rougier, P., Degott, C., Rueff, B. and Benhamou, J.-P. (1978). Nodular regenerative hyperplasia of the liver. Report of six cases and review of the literature. Gastroenterology, 75, 169–172

    PubMed  CAS  Google Scholar 

  38. Wanless, I. R. (1990). Micronodulartransformation (nodular regenerative hyperplasia) of the liver: a report of 64 cases among 2,500 autopsies and a new classification of benign hepatocellular nodules. Hepatology, 11,787–797

    Article  PubMed  CAS  Google Scholar 

  39. Weinbren, K. and Washington, S. L. A. (1976). Hyperplastic nodules after portacaval anastomosis in rats. Nature (London), 264, 440–442

    Article  CAS  Google Scholar 

  40. Stromeyer, F. W. and Ishak, K. G. (1981). Nodular transformation (nodular ‘regenerative’ hyperplasia) of the liver. A clinicopathological study of 30 cases. Hum. Pathol., 12,60–71

    CAS  Google Scholar 

  41. Sherlock, S., Feldman, C. A., Moran, B. and Scheuer, P. J. (1966). Partial nodular transformation of the liver with portal hypertension. Am. J. Med., 40, 195–203

    Article  PubMed  CAS  Google Scholar 

  42. Wanless, I. R., Lentz, J. S. and Roberts, E. A. (1985). Partial nodular transformation of the liver in an adult with persistent ductus venosus. Review with hypothesis on pathogenesis. Arch. Pathol. Lab. Med., 109, 427–432

    PubMed  CAS  Google Scholar 

  43. Shedlofsky, S., Koehler, R. E., DeSchryver-Keckskemetir, K. and Alpers, D. H. (1980). Non-cirrhotic nodular transformation of the liver with portal hypertension. Clinical, angiographic and pathologic correlation. Gastroenterology, 79,938–943

    PubMed  CAS  Google Scholar 

  44. Popovsky, M. A., Costa, J. C. and Doppman, J. L. (1979). Meyenburg complexes of the liver and bile cysts as a consequence of hepatic ischaemia. Hum. Pathol., 10, 425–432

    CAS  Google Scholar 

  45. Allaire, G. S., Rabin, L., Ishak, K. G. and Sesterhenn, I. A. (1988). Bile duct adenoma. A study of 152 cases. Am. J. Surg. Pathol., 12. 708–715

    Article  PubMed  CAS  Google Scholar 

  46. Wheeler, D. A. and Edmondson, H. A. (1985). Cystadenoma with mesenchymal stroma (CMS) in the liver and bile ducts. A clinicopathologic study of 17 cases, 4 with malignant change. Cancer, 56, 1434–1445

    Article  PubMed  CAS  Google Scholar 

  47. Ishak, K. G., Willis, G. W., Cummins, S. D. and Bullock, A. A. (1977). Biliary cystadenoma and cystadeno-carcinoma. Cancer, 39, 322–338

    Article  PubMed  CAS  Google Scholar 

  48. Ishak, K. G. (1976). Primary hepatic tumours in childhood. In Popper, H. and Schaffner, F. (eds). Progr. Liver Dis. V. pp. 636–667. New York: Grune and Stratton

    Google Scholar 

  49. Holcomb, G. W., O’Neill, J. A., Mahboubi, S. and Bishop, H. C. (1988). Experience with hepatic hemangioendothelioma in infancy and childhood. J. Pediatr. Surg., 23, 661–666

    Article  PubMed  Google Scholar 

  50. Srouji, M. N., Chatten, J., Schulman, W. M., Ziegler, M. M. and Koop, C. E. (1978). Mesenchymal hamartoma of the liver in infants. Cancer, 2483–2489

    Google Scholar 

  51. Stocker, J. T. and Ishak, K. G. (1983). Mesenchymal hamartoma of the liver. Pediatr. Pathol., 1, 245–267

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Histopathology, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK

    D. G. D. Wight

Authors
  1. D. G. D. Wight
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 1993 D. G. D. Wight

About this chapter

Cite this chapter

Wight, D.G.D. (1993). Benign Tumours and Tumour-like Conditions. In: Atlas of Liver Pathology. Current Histopathology, vol 23. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-2212-2_22

Download citation

  • DOI: https://doi.org/10.1007/978-94-011-2212-2_22

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-4980-1

  • Online ISBN: 978-94-011-2212-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation