Abstract
The applicability of coupling gas (GC) and supercritical fluid chromatography (SFC) directly to supercritical fluid extraction (SFE) is made inherently easier by the nature of the chromatographic mobile phases employed. For on-line GC analysis, the presence of the supercritical fluid (SF) carbon dioxide in the SFE/chromatographic interface is not a problem since the GC mobile phase itself is a gas. After the analyte is trapped at the head of the column and the decompressed extraction fluid is purged, thermal desorption of the analyte is begun. In SFE-SFC, the same fluid that is used for extraction is likewise used for chromatography. Even though the fluid is decompressed and exists as a gas in the interface, where extracted analyte is focused, raising the pressure and the temperature of the chromatographic mobile phase converts it into a SF once again for SFC.
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© 1993 Springer Science+Business Media Dordrecht
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Howard, A.L., Taylor, L.T. (1993). Supercritical fluid extraction-high performance liquid chromatography: on-line and off-line strategies. In: Westwood, S.A. (eds) Supercritical Fluid Extraction and its Use in Chromatographic Sample Preparation. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-2164-4_6
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DOI: https://doi.org/10.1007/978-94-011-2164-4_6
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