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Endothelium, Lipoproteins and Atherosclerosis. Effects of Lipid Lowering and Lipid Modification Therapy

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Neurohumoral Regulation of Coronary Flow

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 150))

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Abstract

Cholesterol-lowering therapy has been proven to reduce total mortality in post myocardial infarct patients after 15 years of treatment with niacin1. In the Lipid Research Clinics’ study, the treatment with cholestyramin as primary prevention was associated with a lower incidence of angina pectoris and positive exercise tests2. In addition, the coronary artery regression study of Brown showed a reduction in adverse cardiac events in patients with angina treated with hypolipemica, which was as impressive as the regression of atherosclerosis in this group3.

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© 1993 Springer Science+Business Media Dordrecht

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van Boven, A.J., Jukema, J.W. (1993). Endothelium, Lipoproteins and Atherosclerosis. Effects of Lipid Lowering and Lipid Modification Therapy. In: van Gilst, W.H., Lie, K.I. (eds) Neurohumoral Regulation of Coronary Flow. Developments in Cardiovascular Medicine, vol 150. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-1900-9_8

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  • DOI: https://doi.org/10.1007/978-94-011-1900-9_8

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-4839-2

  • Online ISBN: 978-94-011-1900-9

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