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Tracers for Clinical Evaluation of Gliomas: A Neurologist’s View

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PET Studies on Amino Acid Metabolism and Protein Synthesis

Part of the book series: Developments in Nuclear Medicine ((DNUM,volume 23))

Abstract

Positron-labeled amino acids, e.g.11C-methionine or 18F-fluorotyrosine, may be used for clinical evaluation of gliomas. In that context, their potentials and limitations, as far as they are currently known must been seen in comparison with other PET tracers and other tomographic imaging techniques. With regard to spatial resolution - which is always the most important issue when surgical or stereotactic therapy is considered - PET is clearly superior to other isotope imaging techniques, but cannot compete with computed tomography (CT) and magnetic resonance imaging (MRI). Thus, the clinician needs to know, which of the local functional alterations that can be demonstrated with PET add clinically relevant information to what can already be seen with CT and MRI.

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Authors
  1. K. Herholz
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Editor information

Editors and Affiliations

  1. Groupe d’Imagerie Neuro-fonctionelle, Service Hospitalier Frédéric Joliot, CEA-DRIPP Orsay, et Hôpital R. Debré, Paris, France

    B. M. Mazoyer

  2. Max-Planck-Institute for Neurological Research, Cologne, Germany

    W. D. Heiss

  3. E.E.C. Concerted Action on PET Investigations of Cellular Regeneration and Degeneration, Service Hospitalier Frédéric Joliot, Hôpital d’Orsay, Orsay, France

    D. Comar

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© 1993 Springer Science+Business Media Dordrecht

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Herholz, K. (1993). Tracers for Clinical Evaluation of Gliomas: A Neurologist’s View. In: Mazoyer, B.M., Heiss, W.D., Comar, D. (eds) PET Studies on Amino Acid Metabolism and Protein Synthesis. Developments in Nuclear Medicine, vol 23. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-1620-6_15

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  • DOI: https://doi.org/10.1007/978-94-011-1620-6_15

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-4706-7

  • Online ISBN: 978-94-011-1620-6

  • eBook Packages: Springer Book Archive

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