Abstract
The nucleolus is the most prominent nuclear organelle. Only one major function is ascribed to the nucleolus: here ribosomal RNA (rRNA) is transcribed, processed and assembled into preribosomal particles (Reeder, 1990 Warner,1990). The growing eukaryotic cell contains thousands of different transcripts, but the nucleolar rRNA synthesis accounts for nearly half of the cellular transcriptional activity. Besides tandemly repeated rRNA genes, the presence of more than 100 ribosomal proteins, nucleolar proteins and ribonucleoproteins (RNPs) is required for the nucleolar function, including RNA polymerase I, DNA topoisomerases, transcription factors, processing enzymes, 5S rRNA and U3, U8, U13 and U14 small nucleolar RNAs (snoRNAs) (Reeder, 1990 Warner,1990).
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© 1993 Springer Science+Business Media Dordrecht
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Raska, I., Dundr, M. (1993). Compartmentalization of the cell nucleus: case of the nucleolus. In: Chromosomes Today. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-1510-0_8
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DOI: https://doi.org/10.1007/978-94-011-1510-0_8
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