Skip to main content
SpringerLink
Log in

Basic Immunology

  • Chapter
Book cover Immunology of ENT Disorders

Part of the book series: Immunology and Medicine Series ((IMME,volume 23))

  • 107 Accesses

Abstract

Survival of the individual depends on protection from pathogenic organisms, including protozoa, bacteria, viruses and fungi. This protection of the integrity of the individual is the major function of the immune system. Failure of components within the system results in a wide variety of immunodeficiency-associated diseases, frequently recurrent infections. The problems associated with immunodeficiency are explored further in the following chapter.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Lucas AM, Douglas LC. Principles underlying ciliary activity is the respiratory tract. Arch Otolaryngol. 1934;20:518–41

    Article  Google Scholar 

  2. Jeffery PK, Reid L. Electron microscopy of rat airway.1 Anat. 1975;120:295–320

    CAS  Google Scholar 

  3. Petruson B, Hanson HA, Karlsson G. Structural and functional aspects of cells in the nasal mucociliary system. Arch Otolaryngol. 1984;110:576–81

    Article  PubMed  CAS  Google Scholar 

  4. Rutland J, Cole PJ. Non-invasive sampling of nasal cilia for measurement of beat frequency and study of architecture. Lancet. 1980;2:564–5

    Article  PubMed  CAS  Google Scholar 

  5. Greenstone M, Logan-Sinclair R, Cole PJ. An automated method of recording nasal ciliary beat frequency. IRCS Med Sci. 1984;12:715–6

    Google Scholar 

  6. Holmstrom M, Lund VJ, Scadding GK. Nasal ciliary beat frequency following nasal allergen challenge. Am J Rhinol. 1992;6:101–5

    Article  Google Scholar 

  7. Holmberg K, Pipkorn U. Mucociliary transport in the human nose. Effect of topical glucocorticoid treatment. Rhinology. 1985;23:181–5

    PubMed  CAS  Google Scholar 

  8. Eid NS, Kravath RE, Lanks KW. Heat shock protein synthesis by human polymorphonuclear cells. J Exp Med. 1987;165:1148–52

    Article  Google Scholar 

  9. Worthen GS. Lipid mediators, neutrophils and endothelial injury. Am Rev Resp Dis. 1987;136:455–8

    Article  PubMed  CAS  Google Scholar 

  10. Smedly LA, Tonnesen MG, Sandhaus RA, et al. Neutrophil-mediated injury to endothelial cells. Enhancement by endotoxin and essential role of neutrophil elastase. J Clin Invest. 1986;77:1233–43

    Article  PubMed  CAS  Google Scholar 

  11. Nourshargh S, Rampart M, Hellewell PG, et al. Accumulation of 111In-neutrophils in rabbit skin in allergic and non-allergic inflammatory reactions in vitro with a monoclonal antibody recognising the CD18 antigen. J Immunol. 1989;142:3193–8

    PubMed  CAS  Google Scholar 

  12. Scadding GK, Lund VJ, Navas-Romero J, Darby YC, Seymour N, Turner MW. IgG3 subclass deficiency in chronic rhinosinusitis. Rhinology. 1994; 32: 15–19

    PubMed  CAS  Google Scholar 

  13. Tonegawa S. Somatic generation of antibody diversity. Nature. 1983;302:575

    Article  PubMed  CAS  Google Scholar 

  14. Yancopoulos GD, Alt FW. Regulation of the assembly and expression of variable region genes. Annu Rev Immunol. 1986;4:339

    Article  PubMed  CAS  Google Scholar 

  15. Alt FW, Blackwell TK, Depinho RA, et al. Regulation of genome rearrangement events during lymphocyte differentiation. Immunol Rev. 1987;89:5

    Article  Google Scholar 

  16. AllisonJPLanier LL. The structure, function and serology of the T-cell antigen receptor complex. Annu Rev Immunol. 1987;5:503

    Article  PubMed  CAS  Google Scholar 

  17. Ashwell JD, Klausner RD. Genetic and mutational analysis of the T cell antigen receptor. Annu Rev Immunol. 1990;8:139

    Article  PubMed  CAS  Google Scholar 

  18. Matis L. The molecular basis of T cell specificity. Annu Rev Immunol. 1990;8:65

    Article  PubMed  CAS  Google Scholar 

  19. Clevers H, AlarconBWileman T, et al. The T cell receptor/CD3 complex: a dynamic protein ensemble. Annu Rev Immunol. 1988;6:629

    Article  PubMed  CAS  Google Scholar 

  20. Ahmed A, Smith AH. Surface markers, antigens and receptors on murine T and B cells. CRC Crit Rev Immunol. 1983;4:19

    CAS  Google Scholar 

  21. Muller-Eberhard HJ. The membrane attack complex of complement. Annu Rev Immunol. 1986;4:503

    Article  PubMed  CAS  Google Scholar 

  22. Porter RR, Reid KBM. Activation of the complement system by antigen-antibody complexes: the classical pathway. Adv Protein Chem. 1979;33:1

    Article  PubMed  CAS  Google Scholar 

  23. Fearon DT. Activation of the alternative complement pathway. CRC Crit Rev Immunol. 1979;1:1

    PubMed  CAS  Google Scholar 

Download references

Authors
  1. P. Fitzharris
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Royal National Throat, Nose & Ear Hospital, Gray’s Inn Road, London, UK

    G. K. Scadding (Consultant Rhinologist) (Consultant Rhinologist)

Rights and permissions

Reprints and permissions

Copyright information

© 1994 Springer Science+Business Media Dordrecht

About this chapter

Cite this chapter

Fitzharris, P. (1994). Basic Immunology. In: Scadding, G.K. (eds) Immunology of ENT Disorders. Immunology and Medicine Series, vol 23. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-1436-3_1

Download citation

  • DOI: https://doi.org/10.1007/978-94-011-1436-3_1

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-4629-9

  • Online ISBN: 978-94-011-1436-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation