Abstract
Using primary sequence analysis and experimental data, 3D models of G protein-coupled receptors have been defined. They allow a qualitative description of the neurotransmitter binding site and represent a source of novel, important working hypotheses. A number of experimental results have already validated the model.
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© 1994 Springer Science+Business Media Dordrecht
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Hibert, M.F., Trumpp-Kallmeyer, S., Hoflack, J. (1994). Receptor-Ligand Interactions in Pharmacology and Drug Design. In: Wipff, G. (eds) Computational Approaches in Supramolecular Chemistry. NATO ASI Series, vol 426. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-1058-7_10
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