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Rejection and Tolerance pp 79–93Cite as

Risk Factors for Rejection and Predictive Factors for Chronic Rejection in Kidney Transplantation

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Part of the book series: Transplantation and Clinical Immunology ((TRAC,volume 25))

Abstract

To know the risk of rejection is one of the main goal for each physician in charge of transplanted patients. Such a knowledge should allow us to adapt the immunosuppressive therapy to the level of risk and to avoid to add several high risk factors for the same allogenic kidney recipient. In the litterature two methods are used : to look for risk factors in homogeneous but small one-center studies or in heterogeneous multi-center studies with a large contingent of patients. Risk factors for rejection in kidney transplantation can be classified in four groups : risk factors peculiar to the donor, to the recipient, to the couple donor-recipient and to the post-transplant period. Risk factors related to the donor are age, sex and living or cadaver status. Risk factors related to the recipient are age, sex, race, primary disease, HLA antigens, blood transfusions prior to transplantation and immunization. Risk factors related to the couple donor-recipient are ABO and HLA compatibilities, cold ischemia and delayed graft function, crossmatch procedures. Risk factors related to the evolution of the graft are the short term evolution, infections with cytomegalovirus (CMV), immunosuppression and quality of care.

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Authors
  1. Patrice Deteix
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  2. Christine Carrias
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  3. Eliane Albuisson
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Editor information

J. L. Touraine J. Traeger H. Bétuel J. M. Dubernard J. P. Revillard C. Dupuy

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© 1994 Springer Science+Business Media Dordrecht

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Deteix, P., Carrias, C., Albuisson, E. (1994). Risk Factors for Rejection and Predictive Factors for Chronic Rejection in Kidney Transplantation. In: Touraine, J.L., Traeger, J., Bétuel, H., Dubernard, J.M., Revillard, J.P., Dupuy, C. (eds) Rejection and Tolerance. Transplantation and Clinical Immunology, vol 25. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-0802-7_8

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  • DOI: https://doi.org/10.1007/978-94-011-0802-7_8

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-4345-8

  • Online ISBN: 978-94-011-0802-7

  • eBook Packages: Springer Book Archive

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