Abstract
The field of organ transplantation has grown dramatically over the last 35 years, and one of the key advances that has led to this growth is the introduction of Cyclosporin A as an effective immunosuppressive agent (1). So successful has allotransplantation become with improvement in terms of survival (2), quality of life (3, 4) and cost benefit (5) that ever greater numbers of patients are being referred by physicians for consideration of transplantation. This has resulted in a relative shortage in the number of donor organs and in no area is this more marked than in the field of cardiopulmonary transplantation. In the United Kingdom 454 patients received thoracic organ transplants in the year ending 31 December 1992 while the waiting list grew to 706 patients (6) and the number of patients passing through the assessment procedure is more than three times that number. 25 — 30% of patients waiting for heart or lung transplants die before suitable organs become available for them.
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© 1994 Springer Science+Business Media Dordrecht
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Dunning, J., White, D., Wallwork, J. (1994). Transgenic pigs as potential donors for xenografts. In: Touraine, J.L., Traeger, J., Bétuel, H., Dubernard, J.M., Revillard, J.P., Dupuy, C. (eds) Rejection and Tolerance. Transplantation and Clinical Immunology, vol 25. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-0802-7_14
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DOI: https://doi.org/10.1007/978-94-011-0802-7_14
Publisher Name: Springer, Dordrecht
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