Abstract
Theory and computation of non-equilibrium barrier crossing in two dimensions indicate that the onset of relaxation perpendicular to the reaction coordinate occurs at the first maximum of the logarithmic derivative of the survival probability. This is verified by multi-pulse experiments on CO binding to horse-myoglobin. A model potential surface provides semi-quantitative estimates for features of the decay curves resulting from the protein relaxation process.
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© 1994 Springer Science+Business Media Dordrecht
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Agmon, N. (1994). Multidimensional Kramers and the Onset of Protein Relaxation. In: Jortner, J., Levine, R.D., Pullman, B. (eds) Reaction Dynamics in Clusters and Condensed Phases. The Jerusalem Symposia on Quantum Chemistry and Biochemistry, vol 26. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-0786-0_23
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DOI: https://doi.org/10.1007/978-94-011-0786-0_23
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