Abstract
C-reactive protein (CRP) is a member of the pentraxin family of proteins. It consists of five non-covalently bound subunits forming a discoid of 105 000 Da molecular weight. CRP undergoes calcium-dependent binding to phosphorylcholine-containing lipids such as lecithin, lysolecithin and sphingomyelin. This results in the binding of CRP to damaged cell membranes and to the phosphorylcholine-containing capsule of some bacteria. In addition to causing agglutination and precipitation of bacteria, CRP activates the complement cascade.
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© 1995 Springer Science+Business Media Dordrecht
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Ward, T.M. (1995). C-Reactive Protein. In: Ward, T.M. (eds) Proteins and Tumour Markers May 1995. IAKD the Immunoassay Kit Directory, vol 1 / 3 / 3. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-0681-8_29
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DOI: https://doi.org/10.1007/978-94-011-0681-8_29
Publisher Name: Springer, Dordrecht
Print ISBN: 978-0-7923-8862-3
Online ISBN: 978-94-011-0681-8
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