Abstract
CA 15-3 is a 290 000 Da cell surface antigen defined by a heterologous monoclonal antibody system employing two distinct antibodies. The first antibody — 115D8 — is specific for a human milkfat globule membrane antigen, whilst the second — DF3 — was derived by immunization with a membrane enriched fraction from human breast carcinoma. The two epitopes appear to be expressed on a high molecular weight mucin secreted by the malignant cells in carcinoma of the breast and some other related malignancies.
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© 1995 Springer Science+Business Media Dordrecht
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Ward, T.M. (1995). Carbohydrate Antigen CA 15-3. In: Ward, T.M. (eds) Proteins and Tumour Markers May 1995. IAKD the Immunoassay Kit Directory, vol 1 / 3 / 3. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-0681-8_15
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DOI: https://doi.org/10.1007/978-94-011-0681-8_15
Publisher Name: Springer, Dordrecht
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Online ISBN: 978-94-011-0681-8
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