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Neurobiology and Clinical Aspects of the Outer Retina pp 105–131Cite as

Phototransduction, excitation and adaptation

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Abstract

Vertebrate photoreceptors respond to light and transmit electrical signals to secondary neurons. In the dark, a steady current flows into the outer segment. The current is blocked in the light so that the cell elicits a hyperpolarizing response which is the primary phototransduction signal. The mechanisms generating this photoresponse are now well characterized, especially in the case of rod photoreceptors. The phototransduction process consists of an enzyme cascade including; a visual pigment (rhodopsin), a GTP- binding protein (transducin) and an enzyme hydrolyzing cGMP (cGMP-phosphodiesterase).

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Authors
  1. Satoru Kawamura
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Editors and Affiliations

  1. Department of Biology, Imperial College of Science, Technology and Medicine, London, UK

    M. B. A. Djamgoz (Professor of Neurobiology) (Professor of Neurobiology)

  2. International Marine Centre, Oristano, Italy

    S. N. Archer (Senior Research Fellow) (Senior Research Fellow)

  3. Institute of Cybernetics and Biophysics, Italian National Research Council, Genoa, Italy

    S. Vallerga (Senior Researcher) (Senior Researcher)

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© 1995 Springer Science+Business Media Dordrecht

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Kawamura, S. (1995). Phototransduction, excitation and adaptation. In: Djamgoz, M.B.A., Archer, S.N., Vallerga, S. (eds) Neurobiology and Clinical Aspects of the Outer Retina. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-0533-0_5

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  • DOI: https://doi.org/10.1007/978-94-011-0533-0_5

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-4237-6

  • Online ISBN: 978-94-011-0533-0

  • eBook Packages: Springer Book Archive

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