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Advances in Imaging Techniques in Ischemic Heart Disease pp 17–30Cite as

Use of positron emission tomography for the diagnosis and evaluation of ischemic heart disease

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Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 171))

Summary

Positron emission tomography differs from conventional single photon techniques on the basis of basic physical principles, which translate into better image and contrast resolution, and avoidance of soft tissue attenuation. Consequently, PET is more accurate than SPECT. This is of value in myocardial perfusion imaging, particularly in obese patients, when questions are raised about physiological significance of mild coronary lesions, in complex patients, and in those with prior myocardial infarction. The accuracy of PET imaging for the diagnosis of coronary artery disease is about 90%. The physical principles of PET also favor a fully quantitative approach, which may be used to exactly measure myocardial blood flow. The other major indication of cardiac PET is the identification of viable myocardium, for which the most established technique is FDG imaging. This method is sensitive for the detection of viable myocardium but some variability in its specificity has been reported. New techniques which have been used to examine myocardial viability include evaluation of C-11 acetate clearance, quantitation of rubidium washout, and the perfusible tissue index. The examination of cardiac receptor status with PET may become clinically useful in the future.

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Author information

Authors and Affiliations

  1. Department of Cardiology, Cleveland Clinic International Center, USA

    Th. H. Marwick

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  1. Th. H. Marwick
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Editor information

Editors and Affiliations

  1. Department of Cardiology, University Hospital Leiden, Leiden, The Netherlands

    Ernst E. Van Der Wall

  2. Department of Cardiology, Cleveland Clinic Foundation, Cleveland, USA

    Thomas H. Marwick

  3. Department of Diagnostic Radiology, University Hospital Leiden, Leiden, The Netherlands

    Johan H. C. Reiber

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© 1995 Springer Science+Business Media Dordrecht

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Marwick, T.H. (1995). Use of positron emission tomography for the diagnosis and evaluation of ischemic heart disease. In: Van Der Wall, E.E., Marwick, T.H., Reiber, J.H.C. (eds) Advances in Imaging Techniques in Ischemic Heart Disease. Developments in Cardiovascular Medicine, vol 171. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-0365-7_2

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  • DOI: https://doi.org/10.1007/978-94-011-0365-7_2

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-4163-8

  • Online ISBN: 978-94-011-0365-7

  • eBook Packages: Springer Book Archive

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