Abstract
Genetic analyses of inheritance of disease resistance in plants have demonstrated that resistance is often determined by single dominant or semi-dominant loci (1-5). Although many disease resistance genes have been characterized at a classical genetic level, the molecular cloning and biochemical characterization of most disease resistance genes remains to be accomplished (6). In this regard, it is only within the last two years that Johal and Briggs have reported the successful transposon tagging and cloning of the Hml disease resistance gene of maize (7). The Hml resistance locus of maize is a single dominant locus that confers resistance to Cochliobolus carbonum race 1 which is the causal agent of a severe leaf blight and ear mold disease of maize. This pathogen produces the host-specific toxin (HC-toxin) and Hml encoded resistance is also effective against the purified toxin (8). Sequence information has revealed that Hml gene encodes a NADPH-dependent HC toxin reductase.
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References
Crute IR. The genetic bases of relationships between microbial parasites and their hosts. In: Fraser RSS, ed. Mechanisms of Resistance to Plant Diseases. Dordrecht, Netherlands: Martinus Nijhoff/Dr W. Junk Publishers, 1985: 80–142.
de Wit PJGM. Molecular characterization of gene-for-gene systems in plant-fungus interactions and the application of avirulence genes in the control of plant pathogens. In: Ann. Rev. of Phytopathology. 1992: 391–418
Ellingboe AH. Changing concepts in host-pathogen genetics. Ann. Rev. Phytopathol. 1981;19:125–143.
Flor H. Current status of the gene-for-gene concept. Annu. Rev. Phytopathol. 1971;9:275–296.
Keen NT. Gene-for-gene complementarity in plant-pthogen interactions. Annu. Rev. Genet. 1990;24:447–463.
Bennetzen JL, Jones JDG. Approaches and progress in the molecular cloning of plant disease resistance genes. In: Setlow JK, ed. Genetic Engineering: Principles and Methods. New York: Plenum Press, 1992: 99–124. vol 14).
Johal GS, Briggs SP. Reductase activity encoded by the HMI disease resistance gene in maize. Science 1992;258:985–987.
Meeley RB, Johal GS, Briggs SP, Walton JD. A biochemical phenotype for a disease resistance gene of maize. Plant Cell 1992;4:71–77.
Young N. Potential applications of map-based cloning to plant pathology. Phys. Mol. Plant Path. 1990;37:81–94.
Martin GB, Brommonschenkel SH, Chunwongse J, et al. Map-based cloning of a protein kinase gene conferring disease resistance in tomato. Science 1993;262:1432–1436.
Dangl JL. Applications of Arabidopsis thaliana to outstanding issues in plant-pathogen interactions. Int. Rev. Cytol. 1992: 53–83. vol 144.
Dangl J. The major histocompatibility complex a la carte: are there analogies to plant disease resistance genes on the menu? The Plant J. 1992;2(1):3–11.
Debener T, Lehnackers H, Arnold M, Dangl J. Identification and molecular mapping of a single Arabidopsis thaliana locus determining resistance to a phtopathogenic Pseudomonas syringae isolate. Plant J. 1991;1(3):289–302.
Innes R, Bisgrove S, Smith N, Bent A, Staskawicz B, Liu Y. Identification of a disease resistance locus in Arabidopsis that is functionally homologous to the RPG1 locus of soybean. 1993; 4:813–820.
Kunkel B, Bent A, Dahlbeck D, Innes R, Staskawicz B. RPS2, an Arabidopsis disease resistance locus specifying recognition of Pseudomonas syringae strains expressing the avirulence gene avrRpt2. 1993;5:865–875.
Yu G-L, Katagiri F, Ausubel FM. Arabidopsis mutations at the RPS2 locus result in loss of resistance to Pseudomonas syringae strains expressing the avirulence gene avrRpt2. Mol. Plant-Microbe Interact. 1993;6(4):434–443.
Wanner L, Mittal S, Davis K. Recognition of the avirulence gene avrB from Pseudomonas syringae pv. glycinea by Arabidopsis thaliana. MPMI 1993;6(5):582–591.
Bisgrove SR, Simonich M, Smith N, Sattler A, Innes R. A Disease Resistance Gene in Arabidopsis with Specificity for Two Different.Pathogen Avirulence Genes. Plant Cell 1994;6:927–933.
Whalen M, Innes R, Bent A, Staskawicz B. Identification of Pseudomonas syringae pathogens of Arabidopsis thaliana and a bacterial gene determining avirulence on both arabidopsis and soybean. Plant Cell 1991;3:49–59.
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© 1994 Springer Science+Business Media Dordrecht
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Staskawicz, B., Bent, A., Kunkel, B., Dahlbeck, D., Brown, K. (1994). Genetic Analysis of Bacterial Disease Resistance in Arabidopsis and Cloning of the RPS2 Resistance Gene. In: Daniels, M.J., Downie, J.A., Osbourn, A.E. (eds) Advances in Molecular Genetics of Plant-Microbe Interactions. Current Plant Science and Biotechnology in Agriculture, vol 21. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-0177-6_41
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DOI: https://doi.org/10.1007/978-94-011-0177-6_41
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