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Principles of Crystal Growth in Protein Crystallization

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Abstract

Crystals built of protein, virus, DNA and other big biological molecules are needed to study atomic structure and functions of these molecules by X-ray diffraction. Crystals of several thousands of proteins have already been grown and the structures were found1) Despite of evident progress, growing perfect crystals of biological macromolecules allowing structural determination to a resolution, of ca. 2Å, or better still remains an art. Therefore five International Conferences on Crystal Growth of Biological Macromolecules2)3)4)5)6) attracted much attention last decade and many comprehensive overviews have been published (see, e.g 7)8)9)10)11)12)13) and references therein). The aim of this paper is to present an introductory crystal grower’s view on the fundamentals of the subject.

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References

  1. Protein Data Bank, Chemistry Department, Building 555, Brookhaven National Laboratory, P.O. Box 5000, Upton, NY 11973-5000 USA.

    Google Scholar 

  2. R.S. Feigelson (Ed.), International Conference on Crystallization of Biological Macromolecules, in J. Crystal Growth 76 (1986).

    Google Scholar 

  3. R. Giegé, A. Ducruix, J.C. Fontecilla-Camps, R.S. Feigelson, R. Kern and A. McPherson (Eds.), International Conference on Crystallization of Biological Macromolecules, in J. Crystal Growth 90 (1988).

    Google Scholar 

  4. K.B. Ward, G.L. Gillaland, C.E. Bugg, R.S. Feigelson, J. FonticellaCamps, R. Giegé, A. McPherson and F. Rosenberger (Eds.), International Conference on Crystallization of Biological Macromolecules, in J. Crystal Growth 110(1991).

    Google Scholar 

  5. J.J. Stezowski and W. Littke (Eds.), International Conference on Crystallization of Biological Macromolecules, in J. Crystal Growth 122 (1992).

    Google Scholar 

  6. J.P. Glusker (Ed.), International Conference on Crystallization of Biological Macromolecules, in Acta Cryst. Sec. D Biological Crystallography 50, Pt. 4 (1994) 337.

    Google Scholar 

  7. A. McPherson, Preparation and Analysis of Protein Crystals (John Wiley & Sons, New York, 1982).

    Google Scholar 

  8. G.L. Gilland and D.R. Davies, Methods in Enzymology 104 (1984) 370.

    Article  Google Scholar 

  9. T. Arakawa and S.N. Timasheff, Methods in Enzymology 114 (1985) 49.

    Article  CAS  Google Scholar 

  10. C.W. Carter Jr. (Eds.), METHODS. A Comparison to Methods in Enzymology (Academic Press, San Diego, 1990) vol. 1.

    Google Scholar 

  11. P.C. Weber, Advances in Protein Chemistry 41 (1991) 1.

    Article  CAS  Google Scholar 

  12. R. Giegé, B. Lorber and B. Théobald-Dietrich, Acta Cryst. D50 (1994) 339.

    Google Scholar 

  13. A. Ducruix and R. Giegé (Eds.), Crystallization of Nucleic Acids and Proteins, A Practical Approach (Oxford Univ. Press, New York, 1992).

    Google Scholar 

  14. J.R. Amend, B.F. Mundy and M.T. Azmold, General Organic and Biological Chemistry (Saunders College Publ., Forth Worth, Phil., 1993) p. 698.

    Google Scholar 

  15. C.H. Schein, Biotechnology 8 (1990) 308.

    Article  CAS  Google Scholar 

  16. G.D. Rose, A.R. Geselowitz, G.J. Lesser, R.H. Lee and M.H. Zehfus, Science 229 (1985) 834.

    Article  CAS  Google Scholar 

  17. J. Janin, Nature 277 (1979) 491.

    Article  CAS  Google Scholar 

  18. J. Fauchére, M. Charton, L.B. Kier, A. Verloop and V. Pliska, Int. J. Pept. Prot. Res 32 (1988) 269.

    Article  Google Scholar 

  19. M. Ataka and S. Tanaka, Biopolymers 25 (1986) 337.

    Article  CAS  Google Scholar 

  20. E. Cacioppo and M.L. Pusey, J. Crystal Growth 110 (1991) 66.

    Article  CAS  Google Scholar 

  21. L.A. Monaco and F. Rosenberger, J. Crystal Growth 129 (1993) 465.

    Article  CAS  Google Scholar 

  22. E. Forsythe and M.L. Pusey, J. Crystal Growth 139 (1994) 89.

    Article  CAS  Google Scholar 

  23. M. Riés-Kautt and A. Ducruix, Acta Cryst. D50 (1994) 366.

    Google Scholar 

  24. S.H. Pine, J.B. Hendrickson, D.J. Cram and G.S. Hammond, Organic Chemistry (McGraw Hill, London, 1981).

    Google Scholar 

  25. R. Wolfenden, L. Andersson, P.M. Cuius and C.C. Southgate, Biochemistry 20 (1981) 849.

    Article  CAS  Google Scholar 

  26. C. Tanford and M.L. Wagner, J. Am. Chem. Soc. 76 (1954) 3331.

    Article  CAS  Google Scholar 

  27. C. Tanford and R. Roxby, Biochem. 11 (1972) 2192.

    Article  CAS  Google Scholar 

  28. A.V. Elgersma, M. Ataka and T. Katsura, J. Crystal Growth 122 (1992) 31.

    Article  CAS  Google Scholar 

  29. M. Ataka, Phase Transitions 45 (1993) 205.

    Article  CAS  Google Scholar 

  30. M. Riés-Kautt and A. Ducruix, in: Crystallization of Nucleic Acids and Proteins. Apractical Approach, Eds. A. Ducruix and R. Giegé 1992) vol. p. 195.

    Google Scholar 

  31. G. Feher and Z. Kam, Methods in Enzymology 114 (1985) 77.

    Article  CAS  Google Scholar 

  32. C. Tanford, Physical Chemistry of Macromolecules (John Wiley & Sons, New York, 1961).

    Google Scholar 

  33. H.R. Mahler and E.H. Cordes, Biological Chemistry (Harper Inter, Tokyo, 1966) p. 57.

    Google Scholar 

  34. Z. Kam, H.B. Shore and G. Feher, J.Mol.Biol. 123 (1978) 539.

    Article  CAS  Google Scholar 

  35. J.B. Cole, M.L. Bryan and W.P. Bryan, Arch. Biochem. Biophys. 130 (1969) 86.

    Article  CAS  Google Scholar 

  36. E.J. Cohn and J.T. Edsall (Eds.), Proteins, Amino Acids and Peptides (Van Nostrand-Reinhold, Princeton, 1943).

    Google Scholar 

  37. A.A. Green, J. Biol. Chem. 95 (1932) 47.

    Google Scholar 

  38. S.D. Durbin and G. Feher, J. Crystal Growth 110 (1991) 41.

    Article  CAS  Google Scholar 

  39. R.B. Gupta and R.A. Heideman, AIChE Journal 36 (1990) 333.

    Article  CAS  Google Scholar 

  40. A. Sillero and J.M. Ribeiro, Analytic. Biochem. 179 (1989) 319.

    Article  CAS  Google Scholar 

  41. J.G. Kirkwood, in: Protein, Amino Asids and Peptides, Ed. E.J. Cohn and J.T. Edsall (Van Nostrand-Reinhold, Princeton, 1943) p. 276.

    Google Scholar 

  42. J.N. Israelachvili, Intermolecular and Surface Forces (Academic Press, London, 1991).

    Google Scholar 

  43. R.C. Weast (Eds.), CRC Handbook of Chemistry and Physics (CRC Press, Boca Raton, Flo., 1986) p. F-31.

    Google Scholar 

  44. S.N. Black and R.J. Davey, J. Crystal Growth 90 (1988) 136.

    Article  CAS  Google Scholar 

  45. S.D. Durbin and G. Feher, J. Crystal Growth 76 (1986) 583.

    Article  CAS  Google Scholar 

  46. A.J. Malkin and A. McPherson, J. Crystal Growth 128 (1993) 1232.

    Article  CAS  Google Scholar 

  47. A.J. Malkin and A. McPherson, Acta. Cryst. D50 (1994) 385.

    CAS  Google Scholar 

  48. A.C.T. North, Acta Cryst. 12 (1959) 512.

    Article  CAS  Google Scholar 

  49. P.G. Vekilov, M. Ataka and T. Katsura, J. Crystal Growth 130 (1993) 317.

    Article  CAS  Google Scholar 

  50. P.G. Vekilov, Progr. Cryst. Growth Charact. Materials 26 (1993) 25.

    Article  CAS  Google Scholar 

  51. M. Riés-Kautt and A. Ducruix, J. Biol. Chem. 264 (1989) 745.

    Google Scholar 

  52. K. Takano, Private communication (1994).

    Google Scholar 

  53. K. Takano and M. Ataka, J. Jpn. Ass. Crystal Growth 21 (1994) 251.

    Google Scholar 

  54. Y. Suzuki, S. Miyashita, H. Komatsu, K. Sato and T. Yagi, Jpn. J. Appl. Phys. 33 (1994) L1568.

    Article  CAS  Google Scholar 

  55. C.E. Kundrot and M. Richards, J. Mol. Biol. 200 (1988) 401.

    Article  CAS  Google Scholar 

  56. K. Gekko and H. Noguchi, J. Phys. Chem. 83 (1979) 2706.

    Article  CAS  Google Scholar 

  57. V. Mikol, E. Hirsch and R. Giegé, J. Mol. Biol. 213 (1990) 187.

    Article  CAS  Google Scholar 

  58. M. Skouri, J.-P. Munch, B. Lorber, R. Giegé and S. Candu, J. Crystal Growth 122 (1992) 14.

    Article  CAS  Google Scholar 

  59. N. Niimura, Y. Minezaki, M. Ataka and T. Katsura, J. Crystal Growth 137 (1994) 671.

    Article  CAS  Google Scholar 

  60. F. Boué, F. Lefaucheux, M.C. Robert and I. Rosenman, J. Crystal Growth 133 (1993) 246.

    Article  Google Scholar 

  61. S. Veesler, S. Marcq, J.P. Lafont, R. Astier and R. Boistelle, Acta Cryst. D50 (1994) 355.

    CAS  Google Scholar 

  62. Y.-C. Kim and A. Myerson, J. Crystal Growth 143 (1994) 79.

    Article  CAS  Google Scholar 

  63. R.M. Ginde and A. Myerson, J. Crystal Growth 116 (1992) 41.

    Article  CAS  Google Scholar 

  64. M.A. van Drunen, R. Finsy, H.G. Merkus, B. Scarlett and G.M. van Rosmalen, J. Crystal Growth 134 (1993) 196.

    Article  Google Scholar 

  65. V.G. Taratuta, A. Holsbach, G.M. Thurston, D. Blankenstein and G.B. Benedek, J. Phys. Chem. 94 (1990) 2140.

    Article  CAS  Google Scholar 

  66. C.R. Berland, G.M. Thurston, M. Kondo, M.L. Bridge, J. Pande, O. Ogun and G.B. Benedek, Proc. Nat. Ac. Sci. USA 89 (1992) 1214.

    Article  CAS  Google Scholar 

  67. W. Eberstein, Y. Georgalis and W. Saenger, J. Crystal Growth 143 (1994) 71.

    Article  CAS  Google Scholar 

  68. W.H. Gallagher and C.K. Woodward, Biopolymers 28 (1989) 2001.

    Article  CAS  Google Scholar 

  69. J.N. Israelachvili and R.M. Pashley, Nature 30 (1982) 341.

    Article  Google Scholar 

  70. L.D. Landau and E.M. Lifschits, Statistical Physics (Pergamon, Oxford, 1980).

    Google Scholar 

  71. A.J. Malkin, J. Chuentg and A. McPherson, J. Crystal Growth 126 (1993) 554.

    Google Scholar 

  72. O. Söhnel, J. Crystal Growth 57 (1982) 101.

    Article  Google Scholar 

  73. A.A. Chernov, Modern Crystallography III (Springer, New York, 1984) vol. 36.

    Book  Google Scholar 

  74. S.D. Durbin, W.E. Carlson and M.T. Saros, J. Phys. D: Appl. Phys. 26 (1993) B128.

    Article  CAS  Google Scholar 

  75. A.A. Chernov, L.N. Rashkovich and A.A. Mkrtchan, J. Crystal Growth 74 (1985) 301.

    Google Scholar 

  76. A.A. Chernov, L.N. Rashkovich, I.L. Smol’sky, Y.G. Kuznetsov, A.A. Mkrtchan and A.A. Malkin, in: Crystal Growth, Ed. E.I. Givargizov 1986) vol. 15, p. 43.

    Google Scholar 

  77. A.A. Chernov, in: Progress in Crystal Growth and Characterization of Materials, Ed. H. Komatsu (Pergamon, New York, 1993) vol. 26, p. 121.

    Google Scholar 

  78. L.N. Rashkovich and B.Y. Shekunov, J. Crystal Growth 100 (1990) 133.

    Article  CAS  Google Scholar 

  79. L.N. Rashkovich and G.T. Moldazhanova, J. Crystal Growth (1995) in print.

    Google Scholar 

  80. P.G. Vekilov, Y.G. Kuznetsov and A.A. Chernov, J. Crystal Growth 102 (1990) 706.

    Article  CAS  Google Scholar 

  81. T. Okubo, Progr. Polym. Sci. 18 (1993) 481.

    Article  CAS  Google Scholar 

  82. T. Matsumoto and H. Inoue, J. Appl. Phys. 74 (1993) 2415.

    Article  CAS  Google Scholar 

  83. W.B. Russel, D.A. Saville, D.A. Schowalter and W.R. Schowalter, Colloidal Disparsions (Cambridge Univ. Press, New York, 1989).

    Book  Google Scholar 

  84. C.C. Yong, R.C. De Mattei, R.S. Feigelson and W.A. Tiller, J. Crystal Growth 90 (1988) 79.

    Article  Google Scholar 

  85. Y.Q. Li, N.J. Tao, J. Pan, A.A. Garcia and S.M. Lindsay, Langmuir 9 (1993) 637.

    Article  CAS  Google Scholar 

  86. G. Kepler and S. Fraden, Phys. Rev. Lett. 73 (1994) 356.

    Article  CAS  Google Scholar 

  87. N. Ise, T. Okubo, M. Sugimura, K. Ito and H.J. Nolte, J. Chem. Phys. 78 (1983) 536.

    Article  CAS  Google Scholar 

  88. I. Sogami and N. Ise, J. Chem. Phys. 81 (1984) 6320.

    Article  Google Scholar 

  89. J.T. Overbeek, J. Chem. Phys. 87 (1987) 4406.

    Article  CAS  Google Scholar 

  90. V.N. Morozov, T.Y. Morozova, E.G. Myachin and G.S. Kachalova, Acta Cryst. B41 (1985) 202.

    CAS  Google Scholar 

  91. T. Matsumoto and T. Okubo, J. Rheol. 35 (1991) 135.

    Article  CAS  Google Scholar 

  92. G. Sazaki, H. Ooshima, J. Kato, Y. Harano and N. Hirokawa, J. Crystal Growth 130 (1993) 357.

    Article  CAS  Google Scholar 

  93. G. Sazaki, S. Aoki, H. Ooshima and J. Kato, J. Crystal Growth 139 (1994) 95.

    Article  CAS  Google Scholar 

  94. G. Sazaki, H. Ooshima and J. Kato, J. Crystal Growth 135 (1994) 199.

    Article  CAS  Google Scholar 

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Chernov, A.A., Komatsu, H. (1995). Principles of Crystal Growth in Protein Crystallization. In: van der Eerden, J.P., Bruinsma, O.S.L. (eds) Science and Technology of Crystal Growth. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-0137-0_24

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  • DOI: https://doi.org/10.1007/978-94-011-0137-0_24

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