Abstract
Blood pressure elevation in hypertensive patients is commonly due to a rise in peripheral vascular resistance and in a minority of patients to an increase in cardiac output. Bearing in mind this pathophysiological background, it appears rational to reduce the elevated blood pressure levels by administering agents which lower or normalize the abnormal elevation of vascular resistances.
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Leonetti G, Rappelli A on behalf of Italian Centers. Pinacidil, hydrochlorothiazide and their combination in the treatment of arterial hypertension. Submitted.
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© 1995 Springer Science+Business Media Dordrecht
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Leonetti, G. (1995). Potassium Channel Openers in Therapy: Current Use and Perspective in Hypertension. In: Godfraind, T., Mancia, G., Abbracchio, M.P., Aguilar-Bryan, L., Govoni, S. (eds) Pharmacological Control of Calcium and Potassium Homeostasis. Medical Science Symposia Series, vol 9. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-0117-2_29
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DOI: https://doi.org/10.1007/978-94-011-0117-2_29
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