Abstract
We have produced monoclonal antibodies (mAbs) against antigens of the freshwater planarian Dugesia (G.) tigrina (Girard) using standard protocols. One of these mAbs, TCEN-49, detects an antigen (TCEN-49Ag) present in most cells of the central area of the body, including the pharynx. Labelled cells seem more related by position than by lineage, suggesting that TCEN-49Ag is involved somehow in the expression of central body positional identity. The spatial and temporal changes in TCEN-49Ag expression during growth/degrowth and regeneration have been monitored and the implications of these results are discussed.
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Bueno, D., Espinosa, L., Soriano, M.A., Batlle, E., Baguñà, J., Romero, R. (1995). TCEN-49, a monoclonal antibody that identifies a central body antigen in the planarian Dugesia (Girardia) tigrina. Implications for pattern formation and positional signalling mechanisms. In: Cannon, L.R.G. (eds) Biology of Turbellaria and some Related Flatworms. Developments in Hydrobiology, vol 108. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-0045-8_42
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DOI: https://doi.org/10.1007/978-94-011-0045-8_42
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