Abstract
Indomethacin (IND) is known to cause gastrointestinal lesions when given in high doses to rats.
This is a summary of a poster presentation
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Benoni, G, Cuzzolin, L, Raimondi, MG and Velo, GP (1984). Indomethacin in-
duced intestinal lesions and fecal flora. In Rainsford, KD and Velo, GP (eds). Side Effects of Anti-Inflammatory/Analgesic Drugs. (New York:Raven Press), p. 103
Bertazzoni Minelli, E, Benoni, G, Berti, T, Deganello, A, Zoppi, G and Gaburro, D (1977). A simplified method for the evaluation of human faecal flora in clinical practice, Helv Paediatr Acta, 32, 471
Veilleux, BG and Rowland, I (1981). Simulation of the rat intestinal ecosys- tem using a two-stage continuous culture system, J Gen Microbiol, 123, 103
Kent, TH, Cardelli, RM and Stamler, FW (1969). Small intestinal ulcers and intestinal flora in rats given indomethacin, Am J Pathol, 45, 237
Robert, A and Asano, T (1977). Resistance of germfree rats to indomethacin induced intestinal lesions, Prostaglandins, 14, 333
Rolfe, RD, Halebian, S and Finegold, SM (1981). Bacterial interference be- tween Clostridium difficile and normal fecal flora, J Infect Dis, 143, 470
Rainsford, KD (1983). Mechanism of intestinal mucosal damage by non- steroidal anti-inflammatory drugs. In: Barbara, L, Miglioli, M and Phillips, SF (eds). New Trends in Pathophysiology and Therapy of the Large Bowel. (Amsterdam Elsevier), p. 207.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1987 MTP Press Limited
About this chapter
Cite this chapter
Benoni, G., Del Soldato, P., Cuzzolin, L., Velo, G.P. (1987). Role of intestinal microflora in maintaining indomethacin-induced intestinal lesions in rats. In: Rainsford, K.D., Velo, G.P. (eds) Side-Effects of Anti-Inflammatory Drugs. Inflammation and Drug Therapy Series, vol 2. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-9775-8_6
Download citation
DOI: https://doi.org/10.1007/978-94-010-9775-8_6
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-9777-2
Online ISBN: 978-94-010-9775-8
eBook Packages: Springer Book Archive