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Future trends in free radical studies

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Book cover Inflammation: Mechanisms and Treatment

Part of the book series: Inflammation: Mechanisms and Treatment ((FTIN,volume 4))

Abstract

Free radical mediated events in vivo, particularly as related to inflammation, have been and are likely to remain for the foreseeable future intimately wedded to the active species derived from molecular oxygen, or, as it is more properly called, dioxygen. Since the discovery of the superoxide dismutating activity of metalloprotein enzymes (SOD) having copper, manganese or iron at their active site, and that of the selenium containing glutathione peroxidase, these ubiquitously occurring endogenous enzymes and the active species they regulate have been the subject of a veritable landslide of investigations1-5. To properly assess future trends at this juncture, I think it is important to have a brief look first at ‘what is what’ in our present knowledge of this Janus-faced role of oxygen centred free radicals in tissue.

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Authors and Affiliations

  1. USA

    W. Huber

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  1. W. Huber
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Editors and Affiliations

  1. Department of Experimental Pathology and Rheumatology, St Bartholomew’s Hospital, London, UK

    D. A. Willoughby (Professor) (Professor)

  2. Department of Pharmacology, Hôpital Cochin, Paris, France

    J. P. Giroud (Professor) (Professor)

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Huber, W. (1980). Future trends in free radical studies. In: Willoughby, D.A., Giroud, J.P. (eds) Inflammation: Mechanisms and Treatment. Inflammation: Mechanisms and Treatment, vol 4. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-9423-8_4

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  • DOI: https://doi.org/10.1007/978-94-010-9423-8_4

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-9425-2

  • Online ISBN: 978-94-010-9423-8

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