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Vagal Osmosensitive Receptors Located in the Small Intestine. Role in Gastric Emptying

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Gastrointestinal Motility

Abstract

Various kinds of receptors (mechanoreceptors, chemoreceptors, thermoreceptors) have been evidenced in the small intestine thanks to single recording techniques (1). We studied recently the intestinal osmosensitivity in anaesthetized cats using the microelectrode technique (2). We concluded that the vagal polymodal receptors were able to signal changes in intraluminal osmotic pressure. These endings are activated both by hypotonic (5–138mosmole) and hypertonic (550–1100mosmole) perfusions. Connected with unmyelinated fibres, they are located close to the epithelium as suggested by the short latency of their responses and by their sensitivity to mucosal stroking.

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Reference

  1. Mei, N. (1983). Sensory structures in the viscera. In: Ottoson, D. (ed). Progress in sensory physiology 4. pp. 1–42 (Springer-Verlag).

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  2. Garnier, L. and Mei, N. (1982). Do true osmoreceptors exist at intestinal level ? J.Physiol.(Lond.), 98, 327–397.

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  3. Hunt, J.N. and Knox, M.T. (1968). Regulation of gastric emptying. In: Handbook of physiology, sect 6, vol 4. pp.1917–1935 (Washington DC)

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© 1984 MTP Press Limited

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Mei, N., Garnier, L., Melone, J. (1984). Vagal Osmosensitive Receptors Located in the Small Intestine. Role in Gastric Emptying. In: Roman, C. (eds) Gastrointestinal Motility. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-9352-1_23

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  • DOI: https://doi.org/10.1007/978-94-010-9352-1_23

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-9354-5

  • Online ISBN: 978-94-010-9352-1

  • eBook Packages: Springer Book Archive

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