Abstract
The role of the pylorus in the regulation of gastric emptying is still controversial. Some authors concluded that the pylorus only acts as the terminal part of the antrum (1–4), whereas other authors found evidence for a more specific function of the pylorus (5–10). We have observed in studies with isolated muscle preparations from canine pylorus that particularly the inner layer of the pyloric ring (inner pylorus) exhibits pronounced individual behaviour when compared with preparations from other regions of stomach and duodenum (11). In extension of these experiments we have now studied isolated muscle preparations from human pylorus.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Thomas, J. E. (1957). Mechanics and regulation of gastric emptying. Physiol. Rev., 37, 453–474
Kelly, K. A. (1981). Motility of the stomach and gastroduodenal junction. In: Johnson, L. R. (ed). Physiology of the Gastrointestinal Tract. Vol. 1, pp. 393–410. (New York: Raven Press)
Pröve, J., and Ehrlein, H.-J. (1978). Studies on the mechanism of gastric emptying in dogs. Pflügers Arch:, 377, Suppl., R27
Pröve, J., and Ehrlein, H.-J. (1982). Motor function of gastric antrum and pylorus for evacuation of low and high viscosity meals in dogs. Gut 23 150–156
Anuras, S., Cooke, A. R., and Christensen, J. (1974). An inhibitory innervation at the gastroduodenal junction. J.Clin.Invest., 54, 529–534
Fisher, R. S., Lipshutz, W., and Cohen, S. (1973). The hormonal regulation of pyloric sphincter function. J.Clin.Invest., 52, 1289–1296
Mir, S., Telford, G. L., Mason, G. R., and Ormsbee, H. S. (1979). Noncholinergic nonadrenergic inhibitory innervation of the canine pylorus. Gastroenterology, 76, 1443–1448
Munk, J. F., Gannaway, R. M., Hoare, M., and Johnson, A. G. (1978). Direct measurement of pyloric diameter and tone in man and their response to cholecystokinin. In: Duthie, H. L. (ed). Gastrointestinal Motility in Health and Disease. pp. 349–356. ( Lancaster: MTP Press )
Phaosawasdi, K., and Fisher, R. S. (1982). Hormonal effects on the pylorus. Amer.J.Physiol., 243 G330 - G335
Schulze-Delrieu, K., and Shirazi, S. S. (1983). Neuromuscular differentiation of the human pylorus. Gastroenterology, 84 287–292
Golenhofen, K., Lüdtke, F. E., Milenov, K., and Siewert, R. (1980). Excitatory and inhibitory effects on canine pyloric musculature. In: Christensen, J. (ed). Gastrointestinal Motility. pp. 203–210. ( New York: Raven Press )
Milenov, K., and Golenhofen, K. (1983). Differentiated contractile responses of gastric smooth muscle to substance P. Pflügers Arch., 397, 29–34
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1984 MTP Press Limited
About this chapter
Cite this chapter
Lüdtke, F.E., Golenhofen, K., Becker, H.D. (1984). Mechanical Activity of Isolated Human Pyloric Muscle, in Comparison with Canine Pylorus. In: Roman, C. (eds) Gastrointestinal Motility. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-9352-1_16
Download citation
DOI: https://doi.org/10.1007/978-94-010-9352-1_16
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-9354-5
Online ISBN: 978-94-010-9352-1
eBook Packages: Springer Book Archive