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Gastrointestinal Motility pp 77–85Cite as

Regulation of Gastric Antral Slow Wave Frequency by Prostaglandins

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Abstract

Metabolism of arachidonate results in the production of several prostaglandin (PGs) by gastric muscles (1–6). The physiological role of PGs in regulating electrical and mechanical behavior is not fully understood. In antral circular muscle, PGs decrease the force of contractions by decreasing maximum depolarization of the slow wave (7). Preliminary observations have suggested that endogenous PGs also regulate slow wave frequency (7). Experiments were conducted to examine the regulatory role of PCs in canine antral muscles. Data relating the motility effects of PGs to a case of human gastric psuedo-obstruction is included.

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Authors
  1. K. M. Sanders
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  2. A. J. Bauer
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  3. N. G. Publicover
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Editor information

Editors and Affiliations

  1. Department of Physiology and Neurophysiology L.A. CNRS 205, Faculty of Sciences St Jérôme, University AIX-MARSEILLE III, 13397, Marseille Cedex 13, France

    Claude Roman (Dr. Sc., Professor of Physiology) (Dr. Sc., Professor of Physiology)

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© 1984 MTP Press Limited

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Sanders, K.M., Bauer, A.J., Publicover, N.G. (1984). Regulation of Gastric Antral Slow Wave Frequency by Prostaglandins. In: Roman, C. (eds) Gastrointestinal Motility. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-9352-1_15

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  • DOI: https://doi.org/10.1007/978-94-010-9352-1_15

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-9354-5

  • Online ISBN: 978-94-010-9352-1

  • eBook Packages: Springer Book Archive

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