Skip to main content

Month of Birth and Gametopathy

An Investigation into Patients with Down’s Klinefelter’s and Turner’s Syndrome

  • Chapter
Mental and Physical Handicaps in connection with Overripeness Ovopathy

Abstract

In many countries, both in the northern and the southern hemisphere, the monthly birth frequency of children with congenital aberrations has been investigated. From these data a striking phenomenon becomes apparent: children with congenital aberrations of the central nervous system, facial clefts, stenoses and atresias of the digestive tract, hip dysplasias, and many other anomalies are born more frequently in the winter and, to a less apparent degree, in the late summer. This ‘seasonal influence’ has already been subject to serious consideration as demonstrated, for instance, by the fact that the British Medical Journal has devoted two editorial articles (1958, 1962) to it, in which it was strongly advised that couples who had already produced one child with anencephaly or spina bifida should limit their following conceptions to the winter months as a means of prophylaxis.

Huize ‘Maria Roepaan’, Observation and Treatment Centre for the Mentally Deficient, Ottersum (L), The Netherlands.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Amelar, R. D. (1966). Infertility in man. F. A. Davis Co., Philadelphia, p. 22.

    Google Scholar 

  • Benda, G. E. (1949). Prenatal maternal factors in mongolism. J. Amer. med. Ass. 139, 979–985.

    CAS  Google Scholar 

  • Bolk, L. (1902). Naar aanleiding der erfelijkheid van tuberculose. Ned. T. Geneesk. 38, 1023–1034.

    Google Scholar 

  • Buchan, A. R. (1962). A study of mongolism in Newcastle-upon-Tyne 1948-59. Med. Offr. 107, 51–54.

    Google Scholar 

  • Buck, C., G. H. Valentine and K. Hamilton (1965). Reproductive performance of mothers of mongols. Amer. J. ment. Defic. 70, 886–893.

    Google Scholar 

  • Buck, G., G. H. Valentine and K. Hamilton (1969). A study of microsymptoms in the parents and sibs of patients with Down’s syndrome. Amer. J ment. Defic. 73, 683–692.

    PubMed  CAS  Google Scholar 

  • Cerbus, G. (1970). Seasonal variation in some mental health statistics: suicides, homicides, psychiatric admissions and institutional placement of the retarded. J. clin. Psychol. 26, 61–63.

    Article  PubMed  CAS  Google Scholar 

  • Collman, R. D. and A. Stoller (1962). A survey of mongoloid births in Victoria Australia, 1942–1957. Amer. J. publ. Hlth. 52, 813–829.

    Article  Google Scholar 

  • Court Brown, W. M., D. G. Harnden, P. A. Jacobs et al. (1964). Abnormalities of the sex chromosome complement in man. Spec. Rep. Ser. med. Res. Coun. (Lond.) No. 305.

    Google Scholar 

  • Cowie, V. and E. Slater (1968). The fertility of mothers of mongols. J. ment. Defic. Res. 12, 196–208.

    PubMed  CAS  Google Scholar 

  • EDITORIAL (1958). Brit. med. J. 1, 695.

    Google Scholar 

  • EDITORIAL (1962). Brit. med.J. 2. 1041.

    Google Scholar 

  • Edwards, J. H. (1961). Seasonal incidence of congenital disease in Birmingham. Ann. hum. Genet. 25, 89–93.

    Article  PubMed  CAS  Google Scholar 

  • Engle, E. T. and M. C. Shelesnyak (1934). First menstruation and subsequent menstrual cycles of pubertal girls. Hum. Biol. 6, 431–453.

    Google Scholar 

  • Eufinger, H. and J. Weikersheimer (1933). Der Einfluss atmosphärischer Vorgänge auf den Eklampsieausbruch. Arch. Gynäk. 154, 15–32.

    Article  Google Scholar 

  • Fitt, A. B. (1941). Seasonal influence on growth function and inheritance. (Educ. Rec. Ser. No 17. New Zealand Council for Educ. Res.). Oxford University Press, London.

    Google Scholar 

  • Frøland, A. (1967). Seasonal dependence in birth of patients with Klinefelter’s syndrome. Lancet ii, 771.

    Google Scholar 

  • Geyer, H. (1941). Die Insuffizienz der Ovarien bei Möttern von Mongoloiden. Z. ges. Neurol. Psychiat. 173, 735–741.

    Article  Google Scholar 

  • Goodenough, F. (1941). Month of birth as related to socio-economic status of parents. J. Genet. Psychol 59, 65–76.

    Google Scholar 

  • Greenberg, R. C. (1963). Two factors influencing the birth of mongols to younger mothers. Med. Offr. 109, 62–64.

    Google Scholar 

  • Gunn, J. and G. Fenton (1969). Epilepsy in prisons: a diagnostic survey. Brit. med. J. 4, 326–328.

    Article  PubMed  CAS  Google Scholar 

  • Hartman, C. G. (1932). Studies in the reproduction of the monkey Macacus rhesus with special reference to menstruation and pregnancy. Contr. Embryol. 23, Carneg. Instn. Publ. No. 433, 38–41.

    Google Scholar 

  • Heller, C. G. and Y. Clermont (1963). Spermatogenesis in man: An estimate of its duration. Science 140, 184–185.

    Article  PubMed  CAS  Google Scholar 

  • Houtte, G. M. A. van (1964). Leuven in 1740, een krisisjaar. Ekonomische, sociale en demografische aspekten. Pro Civitate. Verz. Gesch. reeks in-8° No. 3, p. 183.

    Google Scholar 

  • Huntington, E. (1938). Season of birth. John Wiley & Sons Inc., New York.

    Google Scholar 

  • Ingalls, TH. H. (1947). Etiology of mongolism. Amer. J. Dis. Child. 74, 147–165.

    CAS  Google Scholar 

  • Ingalls, TH. H., J. Babbott and R. Phelbrook (1957). The mothers of mongoloid babies. Amer. J. Obstet. Gynec. 74, 572–581.

    PubMed  CAS  Google Scholar 

  • Jongbloet, P. H. (1968). Overripeness of the egg. Maandschr. Kindergeneesk. 36, 352–366.

    Google Scholar 

  • Jongbloet, P. H. (1969). Overrijpheid van het ovum. Beschouwingen over de etiologie van het syndroom van Goldenhar en aanverwante congénitale dysplasieën. Ned. T. Geneesk. 113,653–665, 1214-1217.

    PubMed  CAS  Google Scholar 

  • Jongbloet, P. H. (1969). The intriguing phenomenon of gametopathy and its disastrous effects on the human progeny. Maandschr. Kindergeneesk. 37, 261–283.

    Google Scholar 

  • Jongbloet, P. H. (1970). Preovulatore of intrafolliculaire overrijpheid bij de mens. Keesings med. Arch. 1582, 8587–8593.

    Google Scholar 

  • Jongbloet, P. H. (1970). An investigation into the occurrence of overripeness ovopathy in the normal population. Maandschr. Kindergeneesk. 38, 228–242.

    PubMed  CAS  Google Scholar 

  • Jongbloet, P. H. (1970). Chromosomal aberrations and month of birth. Lancet ii, 1317–1318.

    Google Scholar 

  • Jongbloet, P. H. and G. M. pacilly (1971). De samenhang tussen maand van geboorte en game-topathie. Tijdschr. Psychiat. 13, 198–236.

    Google Scholar 

  • Kirchoff, H. (1937). Jahreszeiten und Belichtungen in ihren Einfluss auf weibliche Genitalfunktionen. Arch. Gynäk. 163, 141–185.

    Article  Google Scholar 

  • Kobayashi, N., T. Furukawa and T. Takatsu (1968). Congenital anomalies in children with malignancy. Peadiat., jap. 16, 31–37.

    CAS  Google Scholar 

  • König, K. (1959). Der mongolismus. Hippokrates Verlag, Stuttgart.

    Google Scholar 

  • Lande-Champain, L. (1954). The etiology of mongolism. J. Child Psychiat. (N.Y.) 3, 53–69.

    PubMed  CAS  Google Scholar 

  • Lang, T. (1931). Zur Frage Geisteskrankheit und Geburtsmonat. Arch, rassen Biol. 25, 42–57.

    Google Scholar 

  • Leck, I. (1966). Incidence and epidemicity of Down’s syndrome. Lancet ii, 457–460.

    Google Scholar 

  • Lindsten, J. (1963). The nature and origtn of X chromosome aberrations in Turner’s syndrome. A cyto-genetical and clinical study of 57 patients. Almqvist & Wiksell, Stockholm.

    Google Scholar 

  • Lunn, J. E. (1959). A survey of mongol children in Glasgow. Scot. med. J. 4, 368–372.

    PubMed  CAS  Google Scholar 

  • Marmol, J. G., A. L. Scriggins and R. F. Vollman (1969). Mothers of mongoloid infants in the collaborative project. Amer. J. Obstet. Gynec. 104, 533–543.

    PubMed  CAS  Google Scholar 

  • Michael, R. P. and D. Zumpe (1970). Rhythmic changes in the copulatory frequency of rhesus monkeys in relation to the menstrual cycle and a comparison with the human cycle. J. reprod. Fertil. 21, 199–201.

    Article  PubMed  CAS  Google Scholar 

  • Mikamo, K. (1968). Intrafollicular overripeness and tératologic development.Cytogenetics 7, 212–233.

    Article  PubMed  CAS  Google Scholar 

  • Miller, D. R., G. J. Newstead and L. W. Young (1969). Perinatal leukemia with a possible variant of the Ellis-van Creveld syndrome. J. Pediat. 74, 300–303.

    Article  PubMed  CAS  Google Scholar 

  • Miller, R. W. (1969). Childhood cancer and congenital defects. A study of US death certificates during the period 1960–1966. Pediat. Res. 3, 389–397.

    Article  PubMed  CAS  Google Scholar 

  • Mills, C. A. (1941). Mental and physical development as influenced by season of conception. Hum. Biol. 13, 378–389.

    Google Scholar 

  • Nielsen, J. and U. Friedrich (1969). Seasonal variation in non-disjunction of sex chromosomes. Hum. Genet. 8, 258–260.

    Article  CAS  Google Scholar 

  • Offord, D. R. and L. A. Cross (1969). Behavioral antecedents of adult schizophrenia. Arch, gen, Psychiat. 21, 267–283.

    CAS  Google Scholar 

  • Øster, J. (1953). Mongolistn. Danish Science Press Ltd., Copenhagen.

    Google Scholar 

  • Pasamanick, B. and H. Knobloch (1958). Seasonal variation in complications of pregnancy. J. Obstet. Gynec. 12, 110–112.

    Article  CAS  Google Scholar 

  • Penrose, L. S. (1954). The distal triradius t on the hands of parents and sibs of mongol imbeciles. Ann. hum. Genet. 19, 10–38.

    Article  PubMed  CAS  Google Scholar 

  • Petersen, W. F. (1934). The seasonal trend in the conception of malformations. Amer. J. Obstet. Gynec. 28, 443–445.

    Google Scholar 

  • Priest, J. H. (1969). Parental dermatoglyphs in age-independent mongolism. J. med. Genet. 6, 304–309.

    Article  PubMed  CAS  Google Scholar 

  • Race, R. R. and R. Sänger (1969). Xg and sex-chromosome abnormalities. Brit. med. Bull 25, 99–103.

    PubMed  CAS  Google Scholar 

  • Record, R. G. and A. Smith (1955). Incidence, mortality and sex distribution of mongoloid defectives. Brit. J. prev. soc. Med. 9, 10–15.

    CAS  Google Scholar 

  • Robinson, A., W. B. Goad, TH. T. Puck et al. (1969). Studies on chromosomal nondisjunction in man. III. Amer. J. hum. Genet. 21, 466–485.

    PubMed  CAS  Google Scholar 

  • Rochford, J. M., T. Detre, G. J. Tucker et al. (1970). Neuropsychological impairments in functional psychiatric diseases. Arch. gen. Psychiat. 22, 114–119.

    PubMed  CAS  Google Scholar 

  • Scheer, W. M. VAN DER (1927). Beiträge zur Kenntnis der mongoloiden Missbildung. Verlag von S. Karger, Berlin.

    Google Scholar 

  • Schneider, L. and K. Immelmann (1969). Tageslänge und Temperatur als regulierende Umweltfaktoren der Keimdrösenreifung beim dreistachligen Stichling. Naturwissenschaften 56, 93.

    Article  PubMed  CAS  Google Scholar 

  • Sigler, A. T., B. H. Cohen, A. M. Lilienfeld et al. (1967). Reproductive and marital experience of parents of children with Down’s syndrome (mongolism). J. Pediat. 70, 608–614.

    Article  PubMed  CAS  Google Scholar 

  • Slatis, H. M. and R. J. DE Cloux (1967). Seasonal variation in stillbirth frequencies. Hum. Biol. 39, 284–294.

    Google Scholar 

  • Smith, A. and R. G. Record (1955). Fertility and reproductive history of mothers of mongoloid defectives. Brit. J. prev. soc. Med. 9, 89–96.

    CAS  Google Scholar 

  • Stark, C. R. and N. Mantel (1967). Lack of seasonal-or temporal-spatial clustering of Down’s syndrome births in Michigan. Amer. J. Epidem. 86, 199–211.

    CAS  Google Scholar 

  • Stieve, H. (1950). Der Ovarialzyklus vom Standpunkt der vergleichenden Anatomie. Naturwissenschaften 37, 8–13.

    Article  Google Scholar 

  • Stott, D. H. (1962). Evidence for a congenital factor in maladjustment and delinquency. Amer. J. Psychiat. 118, 781–794.

    PubMed  CAS  Google Scholar 

  • Timonen, S., B. Franzas and K. Wichmann (1964). Photosensibility of the human pituitary. Ann. Chir. Gynaec. Fenn. 53, 165–172.

    PubMed  CAS  Google Scholar 

  • Timonen, S. and E. Carpen (1968). Multiple pregnancies and photoperiodicity. Ann. Chir. Gynaec. Fenn. 57, 135–138.

    PubMed  CAS  Google Scholar 

  • Tramer, M. (1929). Ãœber die biologische Bedenkung des Geburtsmonates insbesondere för die Psychoseerkrankrung. Arch. Neurol. Psychiat. 24, 17–24.

    Google Scholar 

  • Tönte, W. and H. Niermann (1968). Incidence of Klinefelter’s syndrome and seasonal variation. Lancet i, 641

    Google Scholar 

  • Williams, D. (1969). Neural factors related to habitual aggression. Brain 92, 503–520.

    Article  PubMed  CAS  Google Scholar 

  • Wilmanns, K. (1920). Ãœber die Zunahme des Ausbruchs geistiger StÖrungen in den Fröhjahrsund Sommermonaten. Mönch. med. Wschr. 67, 175–177.

    Google Scholar 

  • Witscm, E. (1952). Overripeness of the egg as a cause of twinning and teratogenesis. Cancer Res. 12, 763–786.

    Google Scholar 

  • Wolda, G. (1929). Interperiodizität. Genetica 11, 453–464.

    Article  Google Scholar 

  • Wolda, G. (1931). Periodicity, rhythm and symmetry with the births. Statistical Communications of the Municipal Bureau of Statistics of Amsterdam, No. 91. J. M. Meulenhof, Amsterdam.

    Google Scholar 

  • Zajaczkowska, K. (1969). Palmar dermatoglyphics in patients with Down’s syndrome and in their parents. Pol. med. J. 8, 1477–1482.

    PubMed  CAS  Google Scholar 

Download references

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 1971 H. E. Stenfert Kroese N. V./Leiden - The Netherlands

About this chapter

Cite this chapter

Jongbloet, P.H. (1971). Month of Birth and Gametopathy. In: Mental and Physical Handicaps in connection with Overripeness Ovopathy. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-2958-2_5

Download citation

  • DOI: https://doi.org/10.1007/978-94-010-2958-2_5

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-90-207-0315-3

  • Online ISBN: 978-94-010-2958-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics