Abstract
The hypothesis that contemporary metabolic pathways evolved from analogous chemical reaction sequences on the primitive Earth leads to a reexamination of models of prebiological phosphorylation. Present-day phosphate uptake by algae and bacteria seems to involve two transport systems: (a) An active transport process occurring at low external phosphate concentrations (as in unpolluted natural waters), with a transport constant K s of 10-7 to 10 M P i . (b) Another (probably diffusive) process at higher phosphate concentrations (> 10-6 M) (as in the interstitial water of reducing sediments). Laboratory model experiments are described for the reaction of reducing sugars with orthophosphate in the presence of cyanogen, producing glycosyl phosphates. These reactions proceed with appreciable yields only at high phosphate concentrations (>10-3 M), and may thus possibly serve as simulations of prebiological phosphorylation with diffusive transport, as it may have occurred in the interstitial water of reducing sediments.
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References
Bartlett, G. R.: 1958, Ann. N.Y. Acad. Sei 75, 110.
Berman, T.: 1970, Limnol. Oceanogr 15, 663.
Bishop, M. J., Lohrmann, R., and Orgel, L. E.: 1972, Nature 237, 162.
Bray, J. T., Bricker, 0. P., and Troup, B. N.: 1973, Science 180, 1362.
Degani, Ch. and Halmann, M.: 1967, Nature 216, 1207.
Degani, Ch. and Halmann, M.: 1971a, J. Chem. Soc. 1459.
Degani, Ch. and Halmann, M.: 1971b, ’Mechanism of the Cyanogen-Induced Phosphorylation of Sugars in Aqueous Solutions’, in Chemical Evolution and the Origin of Life (ed. by R. Buvet and C. Ponnam- peruma ), North Holland Publ., Amsterdam, p. 224.
Degani, Ch. and Halmann, M.: 1972, Nature New Biol. 235, 171.
Deierkauf, F. A. and Booij, H. L.: 1968, Biochim. Biophys. Acta 150, 214.
Gabel, N. W.: 1965, Life Sei. 4, 2085.
Gabel, N. W.: 1972, Perspectives Biol. Medicine 15, 640.
Gabel, N. W. and Ponnamperuma, C.: 1972, in Exobiology (ed. by C. Ponnamperuma) North Holland Publ., Amsterdam, p. 125.
Garen, A. and Otsuji, N.: 1964, J. Mol. Biol 8, 841.
Gaudin, C., Jeanjean, R., and Blasco, F.: 1973, Compt. Rend. Acad. Sei. N.Y. Ill, 301.
Gerdes, H .: 1973, Proc. Austr. Biochem. Soc. 6, 50.
Goodman, J. and Rothstein, A.: 1957, J. Gen. Physiol 40, 915.
Halmann, M., Sanchez, R. A., and Orgel, L. E.: 1969, J. Org. Chem 34, 3702.
Halmann, M. and Stiller, M.: 1974, Limnol. Oceanogr. in press.
Handschuh, G. J., Lohrmann, R., and Orgel, L. E.: 1973, J. Mol. Evolution 2, 251.
Harold, F. M.: 1966, Bacteriol. Rev 30, 772.
Harvey, H. W.: 1957, Chemistry and Fertility of Seawaters Cambridge Univ., p. 96.
Kawatsuji, M.: 1973, Cyanogen-Induced Phosphorylation of D-Fructose, M.Sc. Thesis, Feinberg Graduate School, The Weizmann Institute of Science, Rehovot.
Kunicka-Goldfinger, W. and Kunicki-Goldfinger, W. J. H.: 1972, Acta Microbiol. Polon 4, 49.
Lohrmann, R. and Orgel, L. E.: 1968, Science 161, 64.
Medveczky, N. and Rosenberg, H.: 1970, Bioch. Biophys. Acta 211, 158; 1971, ibid 241, 494.
Miller, S. L. and Parris, M.: 1964, Nature 204
Monod, J .: 1942, Recherches sur la croissance des cultures bacteriennes, Paris, Hermann
Müller, H.: 1972, Arch. Hydrobiol. Suppl. 38, 4, 399.
Oparin, A. I.: 1968, Genesis and Evolutionary Development of Life, Academic Press, New York, p. 95.
Osterberg, R. and Orgel, L. E.: 1972, J. Mol. Evol 1, 241.
Ponnamperuma, C. and Mack, R.: 1965, Science 148, 1221; Abstr. 150th Meeting Amer. Chem. Soc., Atlantic City, C. 44.
Prankerd, T. A. J. and Altman, K. I.: 1954, Biochem. J 58, 622.
Rabinowitz, J., Chang, S., and Ponnamperuma, C.: 1968, Nature 218, 442.
Rabinowitz, J.: 1972, Chimia 26, 350.
Schauer, R. and Hillman, G.: 1961, Hoppe-Seyler’s Z. Physiol. Chem. 325, 9.
Schwartz, A. W.: 1972, Biochim. Biophys. Acta 281, 477.
Schwartz, A. W., van der Veen, M., Bisseling, T., and Chittenden, G. J. F.: 1973, Biosystems 5, 119.
Strickland, J. and Solorzano, L.: 1966, in Some Contemporary Studies in Marine Science (ed. by H. Barnes), Allen and Unwin, London, p. 665.
Taniguchi, H. and Nakamura, M.: 1972, Agr. Biol. Chem 36, 2185, 2373.
Thomas, W. H. and Dodson, A. N.: 1968, Biol. Bull 134, 199.
Waehneldt, T. V. and Fox, S. W.: 1967, Biochim. Biophys. Acta 134, 1.
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Halmann, M. (1974). Models of Prebiological Phosphorylation. In: Oró, J., Miller, S.L., Ponnamperuma, C., Young, R.S. (eds) Cosmochemical Evolution and the Origins of Life. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-2282-8_19
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