Abstract
The lower liminal threshold for light in the fovea was observed under the administration of: (a) 6 g of caffeine and (b) 9 g of calcium lactate placebo. The time-response relationship of the drug effect was observed for 80 min after dosage. The results showed that caffeine produced a highly significant reduction in the luminance necessary for terminal threshold perception. The course of the drug induced change was a decline in threshold luminance during the first 40 to 60 min. The maximum effect for four subjects averaged 0.23 logmL. The drop in threshold was maintained (except for fluctuations) for the remainder of the 80 min test session. Cyclical fluctuations in the response occurred in both control and caffeine conditions. Caffeine also counteracted a decrement in sensitivity which occurred during the latter part of placebo sessions.
This work was supported by research grant NSF G9588 from the National Science Foundation.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Adams, D. Dark adaption (a review of the literature). Medical Research Council, Special Report Series. 1929, No. 127.
Axelrod, J., & Reichenthal, J. The fate of caffeine in man and a method for its estimation in biological material. Journal of Pharmacology and Experimental Therapeutics, 1953, 107, 519–523.
Diamond, A. L. & Cole, R. E. Visual threshold as a function of test area and coffeine administration, Psychonomic Science, 1970, 20, 109–111.
Diamond, A. L., & Gilinsky, A. S. Dark-adaptation luminance thresholds for the resolution of detail following different durations of light adaptation. Journal of Experimental Psychology, 1955, 50 134–143.
Ditchburn, R. W., & Power Steele, E. J. Effect of caffeine and bromide on dark adaption. Nature, 1941, 147, 745–746.
Domey, R. G., McFarland, R. A., & Chadwick, E. Dark adaptation as a function of age and time: II. A derivation. Journal of Gerontology, 1960, 15, 267–282.
Edwards, A. L. Experimental design in psychological research. New York: Rinehart, 1960.
Hansen, J. A., Anderson, E. M. S., & Winterberg, R. P. Studies on dark adaption. V: Effect of various sizes of centrally fixated pre-exposure fields on foveal and peripheral dark adaptation. Journal of the Optical Society of America, 1960, 50, 895–899.
Hecht, S., Haig, C., Chase, A. M. The influence of light adaptation on subsequent dark adaptation of the eye. Journal of General Physiology, 1937, 20, 831–850.
Hecht, S., Hendley, C. D., Frank, S. R., & Haig, C. Anoxia and brightness discrimination. Journal of General Physiology, 1946, 29, 335–351.
Hecht, S., & Mandelbaum, J. The relation between vitamin A and dark adaptation. Journal of the Americal Medical Association, 1939, 112, 1910–1916.
Hecht, S., & Schlaer, S. An adaptometer for measuring human dark adaptation. Journal of the Optical Society of America, 1938, 28, 269–275.
Hillman, B. M. Relationship between stimulus size and threshold intensity in the fovea measured at four exposure times, Journal of the Optical Society of America, 1958, 48, 422–428.
Johannsen, D. E., McBride, P. I., AND Wulfeck, J. W. Studies on dark adaptation. I: The pre-exposure tolerance of the dark-adapted fovea. Journal of the Optical Society of America, 1956, 46, 67–71. (a)
Johannsen, D. E., McBride, P. I., AND Wulfeck, J. W. Studies on dark adaptation. II: The pre-exposure tolerance of the human fovea adapted to different brightness levels. Journal of the Optical Society of America, 1956, 46, 266–269. (b)
Kornetsky, C., Humphries, O., & Evarts, E. V. Comparison of psychological effects of certain centrally acting drugs in man. Archives of Neurology and Psychiatry, 1957, 77, 318–323.
Mandelbaum, J. Dark adaptation: Some physiologic and clinical considerations. Archives of Opthalmology, 1941, 26, 203–239.
McDonald, R. Some basic principles of dark adaptation. Archives of Opthalmology, 1940, 23, 841–851.
McFarland, R. A., & Evans, J. N. Alterations in dark adaptation under reduced oxygen tensions. American Journal of Physiology, 1939, 127, 37–50.
McFarland, R. A., & Fisher, M. B. Alterations in dark adaptation as a function of age. Journal of Gerontology, 1955, 10, 424–428.
McFarland, R. A., & Forbes, W. H. The effects of variations in the concentration of oxygen and of glucose on dark adaptation. Journal of General Physiology, 1940, 24, 69–98.
McFarland, R. A., Roughton, F. J. W., Halperin, M. H., AND Niven, J. I. The effects of carbon monoxide and altitude on visual thresholds. Journal of Aviation Medicine, 1944, 15, 381–394.
Mote, F. A., & Riopelle, A. J. The effect of varying the intensity and the duration of pre-exposure upon foveal dark adaptation in the human eye. Journal of General Physiology, 1951, 34, 651–61 A
National Institute of Health, Psychopharmacology Service Center Bulletin, 1961.
Polyak, S. L. The retina. Chicago: University of Chicago Press, 1941.
Rose, H. W., & Schmidt, I. Factors affecting dark adaptation. Journal of Aviation Medicine, 1947, 18, 218–230.
Stevens, S. S. Handbook of experimental psychology. New York: John Wiley, 1951.
Wald, G., Harper, P. V., Goodman, H. C., & Krieger, H. P. Respiratory effects upon the visual threshold. Journal of General Physiology, 1942, 25, 891–904.
Wertheimer, M. The variability of auditory and visual absolute thresholds in time. Journal of General Psychology, 1955, 52, 111–147.
Winsor, A. L., & Strongin, E. I. A study of the development of tolerance for caffeinated beverages Journal of Experimental Psychology, 1933, 16, 725–734.
Wolf, E., Zigler, M. J., & Cowen-Solomons, H. B. Variability of dark adaptation. Journal of the Optical Society of America, 1960, 50, 961–965.
Wolf, S. Effects of suggestion and conditioning on the action of chemical agents in human subjects - The pharmacology of placebos. Journal of Clinical Investigation, 1950, 29, 100 - 109.
Womack, N. A., & Cole, W. H. Effect of caffeine on basal metabolism. Proceedings of the Society for Experimental Biology and Medicine, 1934, 31, 1248–1250.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1974 D. Reidel Publishing Company, Dordrecht-Holland
About this chapter
Cite this chapter
Diamond, A.L., Smith, E.M. (1974). The Effects of Caffeine on Terminal Dark Adaptation. In: Moskowitz, H.R., Scharf, B., Stevens, J.C. (eds) Sensation and Measurement. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-2245-3_33
Download citation
DOI: https://doi.org/10.1007/978-94-010-2245-3_33
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-2247-7
Online ISBN: 978-94-010-2245-3
eBook Packages: Springer Book Archive