Abstract
A case of a 42-year-old man with a glioblastoma multiforme, who postoperatively was found to present many unusual findings, is reported. The patient’s routine neurological examination showed a right hemiplegia worse in the leg with a very marked grasp reflex in the right hand and mild position sense loss on the right side. There were definite signs of intellectual deterioration.
Writing with the left hand was incorrect, both spontaneously and to dictation, while writing with the right hand was normal except for some disturbances caused by the grasp reflex. He named objects placed in the left hand (concealed from vision) incorrectly; he could select them afterward with his left hand by touch or pointing; and he could draw the object afterward with his left hand. Even while giving an incorrect verbal description, he could demonstrate correctly the use of the object being held in the left hand. If an object was placed in one hand (concealed from vision), he could not select it from a group or draw it with the other hand. He frequently performed verbal commands incorrectly with his left hand.
The authors feel that the simplest explanation of the phenomena is that the patient behaved as if his 2 cerebral hemispheres were disconnected and that the probable cause of this was a lesion of the corpus callosum. Alternative hypotheses and objections are considered, and a brief review is given of relevant earlier clinical observations as well as of the recent work of Sperry on callosal deconnection in animals.
Supported in part by research grants from the National Institutes of Health to the Section of Psychology, Massachusetts Institute of Technology (M-1802) and to the Department of Psychology, Clark University (M-4187), Worcester, Massachusetts.
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Bibliography
Akelaitis, A. J., ‘A Study of Gnosis, Praxis and Language Following Section of the Corpus Callosum and Anterior Commissure’, J. Neurosurg. 1 (1944) 94.
Bouman, L. and GrĂ¼nbaum, A. A., ‘Uber motorischc Momente der Agraphie’, Mschr. Psychial. Neurol. 77 (1930) 223.
Bremer, F., Brihaye, J., and AndrĂ©-Balisaux, G., ‘Physiologie et pathologic du corps Callcux’, Schweiz. Archiv.Neurol. Psychiat. 78 (1956) 31.
Denny-Brown, D., ‘The Nature of Apraxia’, J. Nerv. Mem. Dis. 126 (1988) 9.
Geschwind. N., ‘The Anatomy of Acquired Reading Disorders’, in Reading Disabilities, Johns Hopkins Press, Baltimore, 1962.
Goldstein, K., ‘Zur Lehre von der motorischen Apraxie’. J. Psychol. Neurol. (Lpz.) 11 (1908) 169, 270.
Hécaen, H. and Gimeno-Atava, A., L’apraxie idéomotricc unilatérale gauche’, Rev. Neurol. (Paris) 102 (1960) 648.
Liepmann, H. and Maas, O., ‘Fall von linksseitiger Agraphie und Apraxie bei rechtsseitiger Lähmung’, J. Psychol. Neurol. (Lpz.) 10 (1907) 214.
Maas, O., ‘Ein Fall von linksseitiger Apraxie und Agraphie’, Neurol. Ceniralblati 26 (1907) 789.
Sittig, O., Ăœber Apraxie, Karger, Berlin, 1931.
Sperry, R. W., ‘Cerebral Organization and Behavior’, Science 133 (1961) 1749.
Treacher, J. H. and Ford, F. R., ‘Colloid Cyst of the Third Ventricle’, Arch. Neurol. Psychiat. 37 (1937) 959.
Van Vleuten, C. F., ‘Linksseitige motorischc Apraxie’, Z. Psychial. 64 (1907) 203.
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© 1974 D. Reidel Publishing Company, Dordrecht, Holland
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Geschwind, N. (1974). A Human Cerebral Deconnection Syndrome. In: Selected Papers on Language and the Brain. Boston Studies in the Philosophy of Science, vol 16. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-2093-0_3
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DOI: https://doi.org/10.1007/978-94-010-2093-0_3
Publisher Name: Springer, Dordrecht
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